General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

S C Lewis, C P Warlow, A R Bodenham, B Colam, P M Rothwell, D Torgerson, D Dellagrammaticas, M Horrocks, C Liapis, A P Banning, M Gough, M J Gough, GALA Trial Collaborative Group, Frank C T Smith

Research output: Contribution to journalArticle (Academic Journal)peer-review

407 Citations (Scopus)

Abstract

The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.
Original languageEnglish
Pages (from-to)2132-42
Number of pages11
JournalLancet
Volume372
Issue number9656
DOIs
Publication statusPublished - 20 Dec 2008

Keywords

  • Aged
  • Anesthesia, General
  • Anesthesia, Local
  • Carotid Stenosis
  • Endarterectomy, Carotid
  • Female
  • Humans
  • Male
  • Postoperative Complications
  • Stroke

Fingerprint Dive into the research topics of 'General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial'. Together they form a unique fingerprint.

Cite this