Generalised alopecic and cystic dermatosis in a cat: a counterpart to the hairless mouse phenotype or a unique congenital dermatotis?

AE Neuber, AHM Van den Broek, SM Rhind, PB Hill, KLT Thoday

    Research output: Contribution to journalArticle (Academic Journal)peer-review

    4 Citations (Scopus)

    Abstract

    Abstract A 2-year-old, male neutered, domestic semi-long-haired cat was presented with a 1.5-year history of progressive, initially nonpruritic alopecia and malodorous greasy exudate affecting the distal extremities, trunk and neck but sparing the head and tail. The extensive alopecia and seborrhoea were associated with severe thickening of the skin and fold formation on the dorsal head and distal extremities as well as the lateral thorax and abdomen. The hair was easily epilated, numerous milia were seen on the ventral abdomen and the caudal and lateral thighs, and mild paronychia was present. Histopathological examination of skin biopsies revealed marked cystic dilation of hair follicles and sebaceous glands with follicular hypoplasia, infundibular hyperkeratosis and variable associated inflammation. Systemic glucocorticoid therapy in combination with topical washes with chlorhexidine and miconazole resulted in a marked improvement and some hair regrowth, but the cat was subsequently lost to follow-up. The dermatosis resembles a number of conditions in other species, but it is not clear whether it is a counterpart to the hairless mutant mouse or is a unique dermatosis.
    Translated title of the contributionGeneralised alopecic and cystic dermatosis in a cat: a counterpart to the hairless mouse phenotype or a unique congenital dermatotis?
    Original languageEnglish
    Pages (from-to)63 - 69
    Number of pages7
    JournalVeterinary Dermatology
    Volume17
    DOIs
    Publication statusPublished - Feb 2006

    Bibliographical note

    Publisher: Blackwell
    Other: Clinical paper

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