Genetic prediction of myopia: prospects and challenges

Jeremy Guggenheim, Neema Ghorbani Mojarrad, Cathy Williams, D. Ian Flitcroft

Research output: Contribution to journalArticle (Academic Journal)peer-review

5 Citations (Scopus)
268 Downloads (Pure)


Appeals have been made for eye care professionals to start prescribing anti-myopia therapies as part of their routine management of myopic children. These calls are fuelled by two key considerations. Firstly, that interventions to slow myopia progression have shown success in randomized controlled trials (RCTs), and secondly, appreciation that the risk of sight-threatening complications rises dose-dependently with the level of myopia. Notwithstanding existing gaps in knowledge regarding the efficacy of current treatments, these considerations argue that myopia control interventions should be widely adopted, and that they should be instigated at an early age – especially in children most at risk – in order to reduce the final level of myopia. Therefore in managing a child with myopia, an
eye care professional would have to decide not only which therapy to recommend, but at what age to start treatment. In this review we discuss the future role of genetic prediction in helping clinicians treat myopia.
Original languageEnglish
JournalOphthalmic and Physiological Optics
Early online date23 Aug 2017
Publication statusE-pub ahead of print - 23 Aug 2017

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