Genetic strategies to understand human diabetic nephropathy: wet-lab approaches

Laura Smyth; Katie Kerr; Seamus Duffy; Jill Kilner; Amy McKnight

doi:10.1007/978-1-4939-9841-8_15

Genetic strategies to understand human diabetic nephropathy: wet-lab approaches

Laura Smyth
, Katie Kerr
, Seamus Duffy
, Jill Kilner
, Amy McKnight

Bristol Medical School (PHS)

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

1 Citation (Scopus)

Abstract

Multiple genetic strategies are available to help improve understanding of diabetic nephropathy. This methods chapter provides an overview of phenotype considerations specific to diabetic nephropathy, biobank essentials, and provides detailed methodology for a common benchtop wet-lab approach (Ion Torrent semiconductor sequencing) including in silico genetic variant identification from next generation sequencing data to identify genetic risk factors for diabetic nephropathy.

Original language	English
Title of host publication	Methods in Molecular Biology
Publisher	Springer Nature US
Pages	205-240
Number of pages	36
Volume	2067
DOIs	https://doi.org/10.1007/978-1-4939-9841-8_15
Publication status	Published - 1 Jan 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-1-4939-9841-8_15

https://www.scopus.com/pages/publications/85074685243

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title = "Genetic strategies to understand human diabetic nephropathy: wet-lab approaches",

abstract = "Multiple genetic strategies are available to help improve understanding of diabetic nephropathy. This methods chapter provides an overview of phenotype considerations specific to diabetic nephropathy, biobank essentials, and provides detailed methodology for a common benchtop wet-lab approach (Ion Torrent semiconductor sequencing) including in silico genetic variant identification from next generation sequencing data to identify genetic risk factors for diabetic nephropathy.",

author = "Laura Smyth and Katie Kerr and Seamus Duffy and Jill Kilner and Amy McKnight",

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AU - Kilner, Jill

AU - McKnight, Amy

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AB - Multiple genetic strategies are available to help improve understanding of diabetic nephropathy. This methods chapter provides an overview of phenotype considerations specific to diabetic nephropathy, biobank essentials, and provides detailed methodology for a common benchtop wet-lab approach (Ion Torrent semiconductor sequencing) including in silico genetic variant identification from next generation sequencing data to identify genetic risk factors for diabetic nephropathy.

U2 - 10.1007/978-1-4939-9841-8_15

DO - 10.1007/978-1-4939-9841-8_15

M3 - Chapter in a book

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EP - 240

BT - Methods in Molecular Biology

PB - Springer Nature US

ER -

Genetic strategies to understand human diabetic nephropathy: wet-lab approaches

Abstract

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