Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis

James Yarmolinsky; Emmanouil Bouras; Andrei Constantinescu; Kimberley Burrows; Caroline J Bull; Emma E Vincent; Richard M Martin; Olympia Dimopoulou; Sarah J Lewis; Victor Moreno; Marijana Vujkovic; Kyong-Mi Chang; Benjamin F Voight; Philip S Tsao; Marc J Gunter; Jochen Hampe; Annika Lindblom; Andrew J Pellatt; Paul D P Pharoah; Robert E Schoen; Steven Gallinger; Mark A Jenkins; Rish K Pai; Dipender Gill; Kostas K Tsilidis

doi:10.1101/2022.10.24.22281370

Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis

James Yarmolinsky, Emmanouil Bouras, Andrei Constantinescu, Kimberley Burrows, Caroline J Bull, Emma E Vincent, Richard M Martin, Olympia Dimopoulou, Sarah J Lewis, Victor Moreno, Marijana Vujkovic, Kyong-Mi Chang, Benjamin F Voight, Philip S Tsao, Marc J Gunter, Jochen Hampe, Annika Lindblom, Andrew J Pellatt, Paul D P Pharoah, Robert E SchoenSteven Gallinger, Mark A Jenkins, Rish K Pai, Dipender Gill, Kostas K Tsilidis

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Original language	English
DOIs	https://doi.org/10.1101/2022.10.24.22281370
Publication status	Published - 26 Oct 2022

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Yarmolinsky, J., Bouras, E., Constantinescu, A., Burrows, K., Bull, C. J., Vincent, E. E., Martin, R. M., Dimopoulou, O., Lewis, S. J., Moreno, V., Vujkovic, M., Chang, K.-M., Voight, B. F., Tsao, P. S., Gunter, M. J., Hampe, J., Lindblom, A., Pellatt, A. J., Pharoah, P. D. P., ... Tsilidis, K. K. (2022, Oct 26). Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis. https://doi.org/10.1101/2022.10.24.22281370

@misc{ca2b15e2351345ffaa0e51cf31ae380b,

title = "Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis",

author = "James Yarmolinsky and Emmanouil Bouras and Andrei Constantinescu and Kimberley Burrows and Bull, \{Caroline J\} and Vincent, \{Emma E\} and Martin, \{Richard M\} and Olympia Dimopoulou and Lewis, \{Sarah J\} and Victor Moreno and Marijana Vujkovic and Kyong-Mi Chang and Voight, \{Benjamin F\} and Tsao, \{Philip S\} and Gunter, \{Marc J\} and Jochen Hampe and Annika Lindblom and Pellatt, \{Andrew J\} and Pharoah, \{Paul D P\} and Schoen, \{Robert E\} and Steven Gallinger and Jenkins, \{Mark A\} and Pai, \{Rish K\} and Dipender Gill and Tsilidis, \{Kostas K\}",

year = "2022",

month = oct,

day = "26",

doi = "10.1101/2022.10.24.22281370",

language = "English",

type = "Other",

}

Yarmolinsky, J, Bouras, E, Constantinescu, A, Burrows, K, Bull, CJ, Vincent, EE , Martin, RM , Dimopoulou, O, Lewis, SJ, Moreno, V, Vujkovic, M, Chang, K-M, Voight, BF, Tsao, PS, Gunter, MJ, Hampe, J, Lindblom, A, Pellatt, AJ, Pharoah, PDP, Schoen, RE, Gallinger, S, Jenkins, MA, Pai, RK, Gill, D & Tsilidis, KK 2022, Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis. https://doi.org/10.1101/2022.10.24.22281370

TY - GEN

T1 - Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis

AU - Yarmolinsky, James

AU - Bouras, Emmanouil

AU - Constantinescu, Andrei

AU - Burrows, Kimberley

AU - Bull, Caroline J

AU - Vincent, Emma E

AU - Martin, Richard M

AU - Dimopoulou, Olympia

AU - Lewis, Sarah J

AU - Moreno, Victor

AU - Vujkovic, Marijana

AU - Chang, Kyong-Mi

AU - Voight, Benjamin F

AU - Tsao, Philip S

AU - Gunter, Marc J

AU - Hampe, Jochen

AU - Lindblom, Annika

AU - Pellatt, Andrew J

AU - Pharoah, Paul D P

AU - Schoen, Robert E

AU - Gallinger, Steven

AU - Jenkins, Mark A

AU - Pai, Rish K

AU - Gill, Dipender

AU - Tsilidis, Kostas K

PY - 2022/10/26

Y1 - 2022/10/26

UR - https://doi.org/10.1101/2022.10.24.22281370

U2 - 10.1101/2022.10.24.22281370

DO - 10.1101/2022.10.24.22281370

M3 - Other contribution

ER -

Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis

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