Genetics of smoking behaviour

Jennifer J Ware, Marcus R Munafò

Research output: Contribution to journalArticle (Academic Journal)peer-review

7 Citations (Scopus)

Abstract

It is now well-established that smoking-related behaviours are under a substantial degree of genetic influence. Efforts are now focused on identifying the specific genetic variants which underlie these behaviours. Within this chapter, we introduce a variety of established and emerging methods employed to identify such variants, ranging from candidate gene to whole genome sequencing approaches, and highlight what these techniques have taught us about the genetic architecture of smoking-related behaviours. Further, we discuss how phenotype refinement has developed our understanding of these relationships, affording us insight into the specific mechanisms linking genetic variants to smoking-related behaviours.

Original languageEnglish
Pages (from-to)19-36
Number of pages18
JournalCurrent topics in behavioral neurosciences
Volume23
DOIs
Publication statusPublished - 2015

Structured keywords

  • Brain and Behaviour
  • Tobacco and Alcohol

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