Genome-wide analysis of admixture and adaptation in the Africanized honeybee

Ronald M. Nelson, Andreas Wallberg, Zilá Luz Paulino Simões, Daniel J. Lawson, Matthew T Webster

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)
233 Downloads (Pure)

Abstract

Genetic exchange by hybridization or admixture can make an important contribution to evolution, and introgression of favourable alleles can facilitate adaptation to new environments. A small number of honeybees (Apis mellifera) with African ancestry were introduced to Brazil ~60 years ago, which dispersed and hybridized with existing managed populations of European origin, quickly spreading across much of the Americas in an example of a massive biological invasion. Here, we analyse whole-genome sequences of 32 Africanized honeybees sampled from throughout Brazil to study the effect of this process on genome diversity. By comparison with ancestral populations from Europe and Africa, we infer that these samples have 84% African ancestry, with the remainder from western European populations. However, this proportion varies across the genome and we identify signals of positive selection in regions with high European ancestry proportions. These observations are largely driven by one large gene-rich 1.4-Mbp segment on chromosome 11 where European haplotypes are present at a significantly elevated frequency and likely confer an adaptive advantage in the Africanized honeybee population. This region has previously been implicated in reproductive traits and foraging behaviour in worker bees. Finally, by analysing the distribution of ancestry tract lengths in the context of the known time of the admixture event, we are able to infer an average generation time of 2.0 years. Our analysis highlights the processes by which populations of mixed genetic ancestry form and adapt to new environments.
Original languageEnglish
Pages (from-to)3603-3617
Number of pages15
JournalMolecular Ecology
Volume26
Issue number14
Early online date24 Apr 2017
DOIs
Publication statusPublished - Jul 2017

Keywords

  • Adaptation
  • Admixture
  • Africanized honeybee
  • Biological invasion
  • Introgression
  • Natural selection

Fingerprint Dive into the research topics of 'Genome-wide analysis of admixture and adaptation in the Africanized honeybee'. Together they form a unique fingerprint.

  • Cite this

    Nelson, R. M., Wallberg, A., Simões, Z. L. P., Lawson, D. J., & Webster, M. T. (2017). Genome-wide analysis of admixture and adaptation in the Africanized honeybee. Molecular Ecology, 26(14), 3603-3617. https://doi.org/10.1111/mec.14122