Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort

Ben D Spycher; A J W Henderson; Raquel Granell; David M Evans; George Davey Smith; Nicholas J Timpson; Jonathan A C Sterne

doi:10.1016/j.jaci.2012.06.002

Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort

Ben D Spycher, A J W Henderson, Raquel Granell, David M Evans, George Davey Smith, Nicholas J Timpson, Jonathan A C Sterne

Research output: Contribution to journal › Article (Academic Journal) › peer-review

50 Citations (Scopus)

Abstract

Childhood wheezing and asthma vary greatly in clinical presentation and time course. The extent to which phenotypic variation reflects heterogeneity in disease pathways is unclear.

Original language	English
Pages (from-to)	503-509.e7
Journal	Journal of Allergy and Clinical Immunology
Volume	130
Issue number	2
DOIs	https://doi.org/10.1016/j.jaci.2012.06.002
Publication status	Published - Aug 2012

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10.1016/j.jaci.2012.06.002

http://www.sciencedirect.com/science/article/pii/S0091674912009475

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B603 THE EFFECT OF COMMON DISEASE ASSOCIATED GENETIC VARIANTS ON TRANSCRIPTOMIC AND EARLY LIFE PHENOTYPES
Evans, D. (Principal Investigator)
1/09/08 → 1/09/11
Project: Research
CENTRE FOR CASUAL ANALYSES IN TRANSLATIONAL EPIDEMIOLOGY (CAiTE)
Davey Smith, G. (Principal Investigator)
1/09/07 → 1/09/13
Project: Research
THE NATURAL HISTORY OF ASTHMA AND WHEEZING ILLNESSES FROM BIRTH TO ADOLESCENCE: DETERMINANTS OF THE REMISSION OF ASTHMA
Henderson, A. J. W. (Principal Investigator)
1/10/06 → 1/10/10
Project: Research

Cite this

@article{bb9d6f59e7684e6993b9a8ce53bd6d19,

title = "Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort",

abstract = "Childhood wheezing and asthma vary greatly in clinical presentation and time course. The extent to which phenotypic variation reflects heterogeneity in disease pathways is unclear.",

author = "Spycher, \{Ben D\} and Henderson, \{A J W\} and Raquel Granell and Evans, \{David M\} and Smith, \{George Davey\} and Timpson, \{Nicholas J\} and Sterne, \{Jonathan A C\}",

year = "2012",

month = aug,

doi = "10.1016/j.jaci.2012.06.002",

language = "English",

volume = "130",

pages = "503--509.e7",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Elsevier Inc.",

number = "2",

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T1 - Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort

AU - Spycher, Ben D

AU - Henderson, A J W

AU - Granell, Raquel

AU - Evans, David M

AU - Smith, George Davey

AU - Timpson, Nicholas J

AU - Sterne, Jonathan A C

PY - 2012/8

Y1 - 2012/8

N2 - Childhood wheezing and asthma vary greatly in clinical presentation and time course. The extent to which phenotypic variation reflects heterogeneity in disease pathways is unclear.

AB - Childhood wheezing and asthma vary greatly in clinical presentation and time course. The extent to which phenotypic variation reflects heterogeneity in disease pathways is unclear.

U2 - 10.1016/j.jaci.2012.06.002

DO - 10.1016/j.jaci.2012.06.002

M3 - Article (Academic Journal)

C2 - 22846752

SN - 0091-6749

VL - 130

SP - 503-509.e7

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 2

ER -

Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort

Abstract

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Projects

B603 THE EFFECT OF COMMON DISEASE ASSOCIATED GENETIC VARIANTS ON TRANSCRIPTOMIC AND EARLY LIFE PHENOTYPES

CENTRE FOR CASUAL ANALYSES IN TRANSLATIONAL EPIDEMIOLOGY (CAiTE)

THE NATURAL HISTORY OF ASTHMA AND WHEEZING ILLNESSES FROM BIRTH TO ADOLESCENCE: DETERMINANTS OF THE REMISSION OF ASTHMA

Cite this