Has analytical flexibility increased in imaging studies of bipolar disorder and major depression?

M. R. Munafò*, M. J. Kempton

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)
242 Downloads (Pure)

Abstract

There has been extensive discussion of problems of reproducibility of research. Analytical flexibility may contribute to this, by increasing the likelihood that a reported finding represents a chance result. We explored whether analytical flexibility has increased over time, using human imaging studies of bipolar disorder and major depression. Our results indicate that the number of measures collected per study has increased over time for studies of bipolar disorder, but not for studies of major depression.

Original languageEnglish
Pages (from-to)449-451
Number of pages3
JournalPsychological Medicine
Volume45
Issue number3
Early online date25 Jun 2014
DOIs
Publication statusPublished - 12 Feb 2015

Structured keywords

  • Brain and Behaviour
  • Tobacco and Alcohol

Keywords

  • Analytical flexibility
  • bipolar disorder
  • imaging
  • major depression

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  • Projects

    MRC UoB UNITE Unit - Programme 6

    Munafo, M. R. & Munafo, M. R.

    1/06/1331/03/18

    Project: Research

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