Health-related quality of life after minimally invasive oesophagectomy

R Parameswaran, JM Blazeby, R Hughes, K Mitchell, RG Berrisford, SA Wajed

Research output: Contribution to journalArticle (Academic Journal)peer-review

79 Citations (Scopus)


Open oesophagectomy has a detrimental impact on health-related quality of life (HRQL), with recovery taking up to a year. Minimally invasive oesophagectomy (MIO) may enable a more rapid recovery of HRQL.Clinical outcomes from consecutive patients undergoing MIO for cancer were recorded between April 2005 and April 2007. Patients completed validated questionnaires, European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-OES18, before surgery and at 6 weeks, 3, 6 and 12 months after surgery.MIO for cancer or high-grade dysplasia was planned in 62 patients, but abandoned in four owing to occult metastatic disease. Resection was completed in the remaining 58, two having partial conversion to open surgery. There was one in-hospital death and 29 patients developed complications. At 1 year, 52 of 58 patients were alive. Questionnaire response rates were high at each time point (overall compliance 84 per cent). Six weeks after MIO, patients reported deterioration in functional aspects of HRQL and more symptoms than at baseline. However, most improved by 3 months and had returned to baseline levels by 6 months. These levels were maintained 1 year after surgery, with 85 per cent of patients recovering in more than 50 per cent of the HRQL domains.MIO leads to a rapid restoration of HRQL.
Translated title of the contributionHealth-related quality of life after minimally invasive oesophagectomy
Original languageEnglish
Pages (from-to)525 - 531
Number of pages7
JournalBritish Journal of Surgery
Issue number4
Early online date12 Feb 2010
Publication statusPublished - Apr 2010

Bibliographical note

Other: PMID: 20155792


Dive into the research topics of 'Health-related quality of life after minimally invasive oesophagectomy'. Together they form a unique fingerprint.

Cite this