High precision NOEs as a probe for low level conformers-a second conformation of strychnine

Craig P. Butts*, Catharine R. Jones, Jeremy N. Harvey

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

55 Citations (Scopus)

Abstract

A second conformer of strychnine, with a very low population (2.5%), has been identified experimentally, and confirmed by computation, demonstrating the ability of NOE measurements to discriminate minute contributions to dynamic structure ensembles in solution.

Translated title of the contributionHigh precision NOEs as a probe for low level conformers - A second conformation of strychnine
Original languageEnglish
Pages (from-to)1193-1195
Number of pages3
JournalChemical Communications
Volume47
Issue number4
DOIs
Publication statusPublished - 2011

Keywords

  • NMR-SPECTRA

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