Abstract
The facile determination of chemical shift and scalar coupling constants in NMR spectra is often prevented by spectral overlap and limited resolution. Here, we present a high-resolution NMR experiment for the simultaneous detection of both resonance frequencies and coupling patterns even with small J-values. A PSYCHE-decoupled DIAG (Pure Shift Yielded by Chirp Excitation- DIAGonal) experiment, which resolves chemical shift in the indirect dimension of a 2D experiment is combined with real-time J-upscaling in order to visualize small coupling constants that would otherwise be hidden in the linewidth of a regular proton or DIAG spectrum.
Original language | English |
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Pages (from-to) | 3166-3170 |
Number of pages | 5 |
Journal | ChemPhysChem |
Volume | 19 |
Issue number | 22 |
Early online date | 19 Oct 2018 |
DOIs | |
Publication status | Published - 19 Nov 2018 |
Keywords
- homonuclear decoupling
- NMR spectroscopy
- pure shift
- scalar coupling
- structure determination