Home-based reach-to-grasp training for people after stroke: study protocol for a feasibility randomized controlled trial

Ailie J. Turton*, Paul Cunningham, Emma Heron, Frederike van Wijck, Cath Sackley, Chris Rogers, Keith Wheatley, Sue Jowett, Steven L. Wolf, Paulette van Vliet

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Abstract

Background: This feasibility study is intended to assess the acceptability of home-based task-specific reach-to-grasp (RTG) training for people with stroke, and to gather data to inform recruitment, retention, and sample size for a definitive randomized controlled trial.

Methods/design: This is to be a randomized controlled feasibility trial recruiting 50 individuals with upper-limb motor impairment after stroke. Participants will be recruited after discharge from hospital and up to 12 months post-stroke from hospital stroke services and community therapy-provider services. Participants will be assessed at baseline, and then electronically randomized and allocated to group by minimization, based on the time post-stroke and extent of upper-limb impairment. The intervention group will receive 14 training sessions, each 1 hour long, with a physiotherapist over 6 weeks and will be encouraged to practice independently for 1 hour/day to give a total of 56 hours of training time per participant. Participants allocated to the control group will receive arm therapy in accordance with usual care. Participants will be measured at 7 weeks post-randomization, and followed-up at 3 and 6 months post-randomization. Primary outcome measures for assessment of arm function are the Action Research Arm Test (ARAT) and Wolf Motor Function Test (WMFT). Secondary measures are the Motor Activity Log, Stroke Impact Scale, Carer Strain Index, and health and social care resource use. All assessments will be conducted by a trained assessor blinded to treatment allocation. Recruitment, adherence, withdrawals, adverse events (AEs), and completeness of data will be recorded and reported.

Discussion: This study will determine the acceptability of the intervention, the characteristics of the population recruited, recruitment and retention rates, descriptive statistics of outcomes, and incidence of AEs. It will provide the information needed for planning a definitive trial to test home-based RTG training.

Trial registration: ISRCTN56716589

Original languageEnglish
Article number109
Number of pages10
JournalTrials
Volume14
DOIs
Publication statusPublished - 25 Apr 2013

Structured keywords

  • BTC (Bristol Trials Centre)
  • Centre for Surgical Research

Keywords

  • RECOVERY
  • RESEARCH PRIORITIES
  • Home
  • SENSITIVITY
  • Rehabilitation
  • Task-specific training
  • THERAPY
  • Stroke
  • Hand
  • Arm
  • PERFORMANCE
  • Occupational therapy
  • REHABILITATION
  • RELIABILITY
  • MOTOR FUNCTION-TEST
  • Grasp
  • Reach
  • Physical therapy
  • MOVEMENT REPRESENTATIONS
  • UPPER EXTREMITY FUNCTION

Cite this

Turton, A. J., Cunningham, P., Heron, E., van Wijck, F., Sackley, C., Rogers, C., Wheatley, K., Jowett, S., Wolf, S. L., & van Vliet, P. (2013). Home-based reach-to-grasp training for people after stroke: study protocol for a feasibility randomized controlled trial. Trials, 14, [109]. https://doi.org/10.1186/1468-6708-14-109