Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

D. Prieto-Alhambra; M.K. Javaid; A. Judge; Joe Maskell; C. Cooper; N.K. Arden; COASt Study Group

doi:10.1136/annrheumdis-2013-204043

Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

D. Prieto-Alhambra, M.K. Javaid, A. Judge, Joe Maskell, C. Cooper, N.K. Arden, COASt Study Group

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

23 Citations (Scopus)

Abstract

OBJECTIVES: Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women undergoing TKA or THA for osteoarthritis. METHODS: Female participants in the General Practice Research Database undergoing a primary TKA or THA from 1986 to 2006 were included. We excluded patients aged

Original language	English
Pages (from-to)	557-563
Number of pages	7
Journal	Annals of the Rheumatic Diseases
Volume	74
Issue number	3
DOIs	https://doi.org/10.1136/annrheumdis-2013-204043
Publication status	Published - Mar 2015

Keywords

Epidemiology
Knee Osteoarthritis
Orthopedic Surgery
Osteoarthritis
Aged
Arthroplasty, Replacement, Hip
Arthroplasty, Replacement, Knee
Cohort Studies
Estrogen Replacement Therapy
Female
Humans
Medication Adherence
Middle Aged
Osteoarthritis, Hip
Osteoarthritis, Knee
Proportional Hazards Models
Prosthesis Failure
Reoperation
Retrospective Studies

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10.1136/annrheumdis-2013-204043

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title = "Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.",

abstract = "OBJECTIVES: Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women undergoing TKA or THA for osteoarthritis. METHODS: Female participants in the General Practice Research Database undergoing a primary TKA or THA from 1986 to 2006 were included. We excluded patients aged ",

keywords = "Epidemiology, Knee Osteoarthritis, Orthopedic Surgery, Osteoarthritis, Aged, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Cohort Studies, Estrogen Replacement Therapy, Female, Humans, Medication Adherence, Middle Aged, Osteoarthritis, Hip, Osteoarthritis, Knee, Proportional Hazards Models, Prosthesis Failure, Reoperation, Retrospective Studies",

author = "D. Prieto-Alhambra and M.K. Javaid and A. Judge and Joe Maskell and C. Cooper and N.K. Arden and Group, {COASt Study}",

year = "2015",

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doi = "10.1136/annrheumdis-2013-204043",

language = "English",

volume = "74",

pages = "557--563",

journal = "Annals of the Rheumatic Diseases",

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Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study. / Prieto-Alhambra, D.; Javaid, M.K.; Judge, A.; Maskell, Joe; Cooper, C.; Arden, N.K.; Group, COASt Study.

In: Annals of the Rheumatic Diseases, Vol. 74, No. 3, 03.2015, p. 557-563.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

AU - Prieto-Alhambra, D.

AU - Javaid, M.K.

AU - Judge, A.

AU - Maskell, Joe

AU - Cooper, C.

AU - Arden, N.K.

AU - Group, COASt Study

PY - 2015/3

Y1 - 2015/3

N2 - OBJECTIVES: Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women undergoing TKA or THA for osteoarthritis. METHODS: Female participants in the General Practice Research Database undergoing a primary TKA or THA from 1986 to 2006 were included. We excluded patients aged

AB - OBJECTIVES: Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women undergoing TKA or THA for osteoarthritis. METHODS: Female participants in the General Practice Research Database undergoing a primary TKA or THA from 1986 to 2006 were included. We excluded patients aged

KW - Epidemiology

KW - Knee Osteoarthritis

KW - Orthopedic Surgery

KW - Osteoarthritis

KW - Aged

KW - Arthroplasty, Replacement, Hip

KW - Arthroplasty, Replacement, Knee

KW - Cohort Studies

KW - Estrogen Replacement Therapy

KW - Female

KW - Humans

KW - Medication Adherence

KW - Middle Aged

KW - Osteoarthritis, Hip

KW - Osteoarthritis, Knee

KW - Proportional Hazards Models

KW - Prosthesis Failure

KW - Reoperation

KW - Retrospective Studies

U2 - 10.1136/annrheumdis-2013-204043

DO - 10.1136/annrheumdis-2013-204043

M3 - Article (Academic Journal)

C2 - 24451241

VL - 74

SP - 557

EP - 563

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

IS - 3

ER -

Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

Abstract

Keywords

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