Skip to content

How the complex pharmacology of the fentanyls contributes to their lethality

Research output: Contribution to journalEditorial

Original languageEnglish
Number of pages2
DateAccepted/In press - 8 Mar 2019
DatePublished (current) - 17 Apr 2019


Fentanyls as a class of drug have pharmacological properties that make them more likely to lead to overdose than other opioids. In addition to their high potency and rapid onset of action these drugs induce respiratory muscle stiffness making it difficult to breath, are less sensitive than heroin to naloxone reversal and may show reduced cross tolerance to other opioids.

    Research areas

  • fentanyl, heroin, muscle stiffness, naloxone, overdose, respiratory depression

Download statistics

No data available



  • Full-text PDF (final published version)

    Rights statement: This is the final published version of the article (version of record). It first appeared online via Wiley at . Please refer to any applicable terms of use of the publisher.

    Final published version, 151 KB, PDF document

    Licence: CC BY


View research connections

Related faculties, schools or groups