Hypothalamic–pituitary–adrenal function during health, major surgery, and critical illness

Research output: Contribution to journalReview article (Academic Journal)peer-review

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The basic constituents of the hypothalamic–pituitary–adrenal (HPA) axis will be familiar to most physicians because the ‘stress response’ is seen after any significant illness, injury, or surgery. However, this article seeks to highlight the substantial advances in understanding that have been made in the last decade and how these may alter treatment and guide future research.
Original languageEnglish
Article numbermkw042
Pages (from-to)16-21
Number of pages6
JournalBJA Education
Issue number1
Early online date21 Jun 2016
Publication statusPublished - Jan 2017


  • Anaesthesia
  • Hormones – glucocorticoid
  • Hormones - corticosteroid


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