IgG4 orbital inflammation in a 5-year-old child presenting as an orbital mass

Freny Boman Kalapesi, Helen Michelle Garrott, Corina Moldovan, Mandy Williams, Athimalaipet Ramanan, Helen Mary Herbert

Research output: Contribution to journalArticle (Academic Journal)peer-review

19 Citations (Scopus)

Abstract

IgG4 is a newly known systemic disorder. It can present as orbital inflammation or as an orbital mass. We describe the case of a 5-year-old child with proptosis and globe dystopia who went on to have an orbital biopsy. Initially this was reported to be idiopathic orbital inflammation. After IgG4-RD was considered in the differential, the orbital biopsy was revisited, immunohistochemistry was done and the patient's serum was tested for IgG subclass levels. IgG4-RD was diagnosed and the patient was subsequently treated with prednisone and mycophenolate and made a good recovery. This is the youngest reported case of IgG4-RD in a child.
Original languageEnglish
Pages (from-to)137-40
Number of pages4
JournalOrbit (Amsterdam, Netherlands)
Volume32
Issue number2
DOIs
Publication statusPublished - Apr 2013

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