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Imidazolium-tagged glycan probes for non-covalent labeling of live cells

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Original languageEnglish
Pages (from-to)4906-4909
Number of pages4
JournalChemical Communications
Issue number27
DateAccepted/In press - 7 Mar 2016
DatePublished (current) - 7 Apr 2016


Selective, bioorthogonal and fast labeling of glycoconjugates in living cells is a major challenge for synthetic and cellular biology. Here we report the use imidazolium tagged-mannosamine derivative (ITag-Man) for the non-covalent, rapid and site-specific labeling of sialic acid containing glycoproteins using commercial N-nitrilotriacetate fluorescent reagents in a range of cell lines.

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  • Bristol BioDesign Institute

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