Immunohistochemical phenotyping of mouse amacrine cell subtypes

Denize Atan*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Abstract

The retina shares its embryological origin with the central nervous system (CNS), so the neural circuitry of the retina has long been considered to be a relatively simple model of the neural networks in the brain, sharing similar morphologies, neurotransmitters, and receptors. Amacrine cells are, by far, the largest group of inhibitory neurons in the retina that also have the most diverse range of phenotypes of any retinal neuron. Here, I describe an approach, using immunolabeling of cryosections, to identify different subclasses of amacrine cell in the mouse retina.

Original languageEnglish
Title of host publicationMouse Retinal Phenotyping
Pages237-248
Number of pages12
Volume1753
DOIs
Publication statusPublished - 2018

Publication series

NameMethods in Molecular Biology
PublisherHumana Press
ISSN (Print)1064-3745

Keywords

  • Amacrine cell
  • Calcium signaling
  • Neurotransmitter
  • Retina
  • Transcription factor

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