Research output per year
Research output per year
Abstract
Background
Women considering immediate breast reconstruction require high-quality information about the likely need for secondary reconstruction and the long-term risk of revisional surgery to make fully informed decisions about different reconstructive options. Such data are currently lacking. This study aimed to explore the impact of reconstruction type on the number of revisions and secondary reconstructions performed 3, 5, and 8 years after immediate breast reconstruction in a large population-based cohort.
Methods
Women undergoing unilateral mastectomy and immediate breast reconstruction for breast cancer or ductal carcinoma in situ in England between 1 April 2009 and 31 March 2015 were identified from National Health Service Hospital Episode Statistics. Numbers of revisions and secondary reconstructions in women undergoing primary definitive immediate breast reconstruction were compared by procedure type at 3, 5, and 8 years after index surgery.
Results
Some 16 897 women underwent immediate breast reconstruction with at least 3 years’ follow-up. Of these, 14 069 had a definitive reconstruction with an implant only (5193), latissimus dorsi flap with (3110) or without (2373) an implant, or abdominal free flap (3393). Women undergoing implant-only reconstruction were more likely to require revision, with 69.5 per cent (747 of 1075) undergoing at least one revision by 8 years compared with 49.3 per cent (1568 of 3180) in other reconstruction groups. They were also more likely to undergo secondary reconstruction, with the proportion of women having further reconstructive procedures increasing over time: 12.8 per cent (663 of 5193) at 3 years, 14.3 per cent (535 of 3752) at 5 years, and 17.6 per cent (189 of 1075) at 8 years.
Conclusion
Long-term rates of revisions and secondary reconstructions were considerably higher after primary implant-based reconstruction than autologous procedures. These results should be shared with patients to support informed decision-making.
Women considering immediate breast reconstruction require high-quality information about the likely need for secondary reconstruction and the long-term risk of revisional surgery to make fully informed decisions about different reconstructive options. Such data are currently lacking. This study aimed to explore the impact of reconstruction type on the number of revisions and secondary reconstructions performed 3, 5, and 8 years after immediate breast reconstruction in a large population-based cohort.
Methods
Women undergoing unilateral mastectomy and immediate breast reconstruction for breast cancer or ductal carcinoma in situ in England between 1 April 2009 and 31 March 2015 were identified from National Health Service Hospital Episode Statistics. Numbers of revisions and secondary reconstructions in women undergoing primary definitive immediate breast reconstruction were compared by procedure type at 3, 5, and 8 years after index surgery.
Results
Some 16 897 women underwent immediate breast reconstruction with at least 3 years’ follow-up. Of these, 14 069 had a definitive reconstruction with an implant only (5193), latissimus dorsi flap with (3110) or without (2373) an implant, or abdominal free flap (3393). Women undergoing implant-only reconstruction were more likely to require revision, with 69.5 per cent (747 of 1075) undergoing at least one revision by 8 years compared with 49.3 per cent (1568 of 3180) in other reconstruction groups. They were also more likely to undergo secondary reconstruction, with the proportion of women having further reconstructive procedures increasing over time: 12.8 per cent (663 of 5193) at 3 years, 14.3 per cent (535 of 3752) at 5 years, and 17.6 per cent (189 of 1075) at 8 years.
Conclusion
Long-term rates of revisions and secondary reconstructions were considerably higher after primary implant-based reconstruction than autologous procedures. These results should be shared with patients to support informed decision-making.
| Original language | English |
|---|---|
| Pages (from-to) | 666–675 |
| Number of pages | 10 |
| Journal | British Journal of Surgery |
| Volume | 110 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 31 Mar 2023 |
Research Groups and Themes
- NIHR ARC West
- Centre for Surgical Research
Keywords
- breast reconstruction
- outcomes
- complications
- revisions
- secondary reconstruction
Fingerprint
Dive into the research topics of 'Impact of procedure type on revision surgery and secondary reconstruction after immediate breast reconstruction in a population-based cohort'. Together they form a unique fingerprint.Research output
- 2 Citations
- 3 Article (Academic Journal)
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Long-term patient-reported outcomes of immediate breast reconstruction after mastectomy for breast cancer: population-based cohort study
Johnson, L. R., White, P., Jeevan, R., Browne, J., Gulliver-Clarke, C., O'Donoghue, J., Mohiuddin, S. G., Hollingworth, W., Fairbrother, P., MacKenzie, M., Holcombe, C. & Potter, S., 1 Dec 2023, In: British Journal of Surgery. 110, 12, p. 1815-1823 9 p., znad276.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Secondary healthcare costs after mastectomy and immediate breast reconstruction for women with breast cancer in England: population-based cohort study
Mohiuddin, S. G., Hollingworth, W., Glynn, J., Jones, T., Johnson, L. R., Potter, S. & The Brighter Steering Group, 1 Sept 2023, In: British Journal of Surgery. 110, 9, p. 1171-1179 9 p., znad149.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Protocol for a national cohort study to explore the long-term clinical and patient-reported outcomes and cost-effectiveness of implant-based and autologous breast reconstruction after mastectomy for breast cancer: The Brighter Study
Johnson, L. R., Holcombe, C., O'Donoghue, J., Jeevan, R., Browne, J., Fairbrother, P., MacKenzie, M., Gulliver-Clarke, C., White, P., Mohiuddin, S. G., Hollingworth, W. & Potter, S., 18 Aug 2021, (E-pub ahead of print) In: BMJ Open. 11, e054055.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile8 Citations (Scopus)46 Downloads (Pure)
Projects
- 1 Finished
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Full Application: The BRIghteR study Breast Reconstruction: InvestigatinG long-term clinical and cost-effectiveness in tHe National MasTectomy and BrEast Reconstruction Audit cohort
Potter, S. (Principal Investigator)
1/04/19 → 23/06/22
Project: Research