Impact of variation in intervention delivery and intervention functions on the effectiveness of behavioural and mood management interventions for smoking cessation in people with depression: protocol for a systematic review and meta-analysis

Gemma Taylor, Paul Aveyard, Regina Van der Meer, Daniel Toze, Bobby Stuijfzand, David Kessler, Marcus Munafo

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)
196 Downloads (Pure)

Abstract

Introduction
Tobacco is the world’s leading preventable cause of disease and death. People with depression are twice as likely to smoke and are less responsive to standard tobacco treatments as compared to the general population. A Cochrane systematic review of randomised controlled trials of smoking cessation treatment for smokers with current or historical depression found that adding mood management to usual smoking treatment improved quit rates. However, the review did not examine if variation in intervention delivery or intervention functions impacted on treatment effectiveness.

With the aim of providing information to develop tailored approaches to treating smoking for people with current depression we will add-on to the Cochrane review in three ways: 1) Use the Template for Intervention Description and Replication checklist to determine if variations in mood management delivery impact on intervention effectiveness, 2) Use the Taxonomy of Behaviour Change Techniques for smoking cessation to examine which behaviour change functions are most effective for smoking cessation in people with current depression, 3) Examine the difference in change in depression scores between intervention and control arms.

Methods and Analysis
We will include randomised controlled trials of smokers with current depression as identified by the previous Cochrane review and the in-progress update of the Cochrane review. We will use meta*regression to examine 1) if variations in delivery of mood management impact on smoking cessation intervention effectiveness, 2) determine which behaviour change functions are most effective for smoking cessation and 3) use meta-analysis of the difference in change in depression scores between treatment arms from baseline to follow-up to determine if offering smoking cessation treatment causes psychological harm.

Ethics and Dissemination
Ethical approval is not required for this study. We will disseminate the findings of this work at conferences, and to relevant patient panels.

Registration details
PROSPERO ID: CRD42017070741
Original languageEnglish
Article numbere018617
Number of pages6
JournalBMJ Open
Volume7
Issue number11
Early online date16 Nov 2017
DOIs
Publication statusPublished - Nov 2017

Structured keywords

  • Jean Golding
  • Bristol Population Health Science Institute
  • Brain and Behaviour
  • Tobacco and Alcohol

Keywords

  • Tobacco
  • Smoking cessation
  • Depression
  • Systematic review
  • Protocol
  • Intervention

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