Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder

Francisco J. Ruiz-Martínez; Elena I. Rodríguez-Martínez; C. Ellie Wilson; Shu Yau; David Saldaña; Carlos M. Gómez

doi:10.1007/s10803-019-04299-0

Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder

Francisco J. Ruiz-Martínez^*, Elena I. Rodríguez-Martínez, C. Ellie Wilson, Shu Yau, David Saldaña, Carlos M. Gómez

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

15 Citations (Scopus)

Abstract

Passive testing of auditory function is an important objective in individuals with ASD due to known difficulties in understanding and/or following task instructions. In present study the habituation to standard tones following deviants and the auditory discriminative processes were examined in two conditions: electronic and human sounds, in a sample of 16 ASD children. ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. MMN amplitude was related to sensory sensitivity. Results suggest an increased activation to repeatedly auditory stimulus and a poor auditory discrimination, for both: electronic and human sounds with consequences on the impaired sensory behavior of ASD subjects.

Original language	English
Pages (from-to)	603-616
Number of pages	14
Journal	Journal of Autism and Developmental Disorders
Volume	50
DOIs	https://doi.org/10.1007/s10803-019-04299-0
Publication status	Published - 15 Nov 2019

Bibliographical note

The acceptance date for this record is provisional and based upon the month of publication for the article.

Structured keywords

SoE Centre for Assessment and Evaluation Research

Keywords

Auditory P1
Autism
Habituation
Mismatch negativity
Sensory perception

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title = "Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder",

abstract = "Passive testing of auditory function is an important objective in individuals with ASD due to known difficulties in understanding and/or following task instructions. In present study the habituation to standard tones following deviants and the auditory discriminative processes were examined in two conditions: electronic and human sounds, in a sample of 16 ASD children. ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. MMN amplitude was related to sensory sensitivity. Results suggest an increased activation to repeatedly auditory stimulus and a poor auditory discrimination, for both: electronic and human sounds with consequences on the impaired sensory behavior of ASD subjects.",

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AU - Ruiz-Martínez, Francisco J.

AU - Rodríguez-Martínez, Elena I.

AU - Wilson, C. Ellie

AU - Yau, Shu

AU - Saldaña, David

AU - Gómez, Carlos M.

N1 - The acceptance date for this record is provisional and based upon the month of publication for the article.

PY - 2019/11/15

Y1 - 2019/11/15

N2 - Passive testing of auditory function is an important objective in individuals with ASD due to known difficulties in understanding and/or following task instructions. In present study the habituation to standard tones following deviants and the auditory discriminative processes were examined in two conditions: electronic and human sounds, in a sample of 16 ASD children. ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. MMN amplitude was related to sensory sensitivity. Results suggest an increased activation to repeatedly auditory stimulus and a poor auditory discrimination, for both: electronic and human sounds with consequences on the impaired sensory behavior of ASD subjects.

AB - Passive testing of auditory function is an important objective in individuals with ASD due to known difficulties in understanding and/or following task instructions. In present study the habituation to standard tones following deviants and the auditory discriminative processes were examined in two conditions: electronic and human sounds, in a sample of 16 ASD children. ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. MMN amplitude was related to sensory sensitivity. Results suggest an increased activation to repeatedly auditory stimulus and a poor auditory discrimination, for both: electronic and human sounds with consequences on the impaired sensory behavior of ASD subjects.

KW - Auditory P1

KW - Autism

KW - Habituation

KW - Mismatch negativity

KW - Sensory perception

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JO - Journal of Autism and Developmental Disorders

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Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder

Abstract

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Keywords

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