Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder

Francisco J. Ruiz-Martínez*, Elena I. Rodríguez-Martínez, C. Ellie Wilson, Shu Yau, David Saldaña, Carlos M. Gómez

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

Abstract

Passive testing of auditory function is an important objective in individuals with ASD due to known difficulties in understanding and/or following task instructions. In present study the habituation to standard tones following deviants and the auditory discriminative processes were examined in two conditions: electronic and human sounds, in a sample of 16 ASD children. ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. MMN amplitude was related to sensory sensitivity. Results suggest an increased activation to repeatedly auditory stimulus and a poor auditory discrimination, for both: electronic and human sounds with consequences on the impaired sensory behavior of ASD subjects.

Original languageEnglish
Pages (from-to)603-616
Number of pages14
JournalJournal of Autism and Developmental Disorders
Volume50
DOIs
Publication statusPublished - 15 Nov 2019

Bibliographical note

The acceptance date for this record is provisional and based upon the month of publication for the article.

Structured keywords

  • SoE Centre for Assessment and Evaluation Research

Keywords

  • Auditory P1
  • Autism
  • Habituation
  • Mismatch negativity
  • Sensory perception

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    Ruiz-Martínez, F. J., Rodríguez-Martínez, E. I., Wilson, C. E., Yau, S., Saldaña, D., & Gómez, C. M. (2019). Impaired P1 Habituation and Mismatch Negativity in Children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 50, 603-616. https://doi.org/10.1007/s10803-019-04299-0