In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections

Gemma M Lasseter; Cliodna A M McNulty; F.D.R Hobbs; David Mant; Paul Little; PRISM Investigators

doi:10.1093/fampra/cmp054

In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections

Gemma M Lasseter, Cliodna A M McNulty, F.D.R Hobbs, David Mant, Paul Little, PRISM Investigators

Research output: Contribution to journal › Article (Academic Journal) › peer-review

24 Citations (Scopus)

Abstract

Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. Although there is no international consensus on the use of RADTs, these kits have been widely adopted in Finland, France and the USA. Yet in the UK, the Clinical Knowledge Summaries, that provide the main online guidance for GPs, discourage RADTs use, citing their poor sensitivity and inability to impact on prescribing decisions in acute sore throat infections.

Original language	English
Pages (from-to)	437-44
Number of pages	8
Journal	Family Practice
Volume	26
Issue number	6
DOIs	https://doi.org/10.1093/fampra/cmp054
Publication status	Published - Dec 2009

Keywords

Group A streptococcus
rapid antigen detection tests
sore throat

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10.1093/fampra/cmp054

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title = "In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections",

abstract = "Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. Although there is no international consensus on the use of RADTs, these kits have been widely adopted in Finland, France and the USA. Yet in the UK, the Clinical Knowledge Summaries, that provide the main online guidance for GPs, discourage RADTs use, citing their poor sensitivity and inability to impact on prescribing decisions in acute sore throat infections.",

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In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections. / Lasseter, Gemma M; McNulty, Cliodna A M; Hobbs, F.D.R; Mant, David; Little, Paul; PRISM Investigators.

In: Family Practice, Vol. 26, No. 6, 12.2009, p. 437-44.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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AU - Mant, David

AU - Little, Paul

AU - PRISM Investigators

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N2 - Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. Although there is no international consensus on the use of RADTs, these kits have been widely adopted in Finland, France and the USA. Yet in the UK, the Clinical Knowledge Summaries, that provide the main online guidance for GPs, discourage RADTs use, citing their poor sensitivity and inability to impact on prescribing decisions in acute sore throat infections.

AB - Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. Although there is no international consensus on the use of RADTs, these kits have been widely adopted in Finland, France and the USA. Yet in the UK, the Clinical Knowledge Summaries, that provide the main online guidance for GPs, discourage RADTs use, citing their poor sensitivity and inability to impact on prescribing decisions in acute sore throat infections.

KW - Group A streptococcus

KW - rapid antigen detection tests

KW - sore throat

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DO - 10.1093/fampra/cmp054

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