In vitro evaluation of five rapid antigen detection tests for group A beta-haemolytic streptococcal sore throat infections

Gemma M Lasseter, Cliodna A M McNulty, F.D.R Hobbs, David Mant, Paul Little, PRISM Investigators

Research output: Contribution to journalArticle (Academic Journal)peer-review

24 Citations (Scopus)

Abstract

Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. Although there is no international consensus on the use of RADTs, these kits have been widely adopted in Finland, France and the USA. Yet in the UK, the Clinical Knowledge Summaries, that provide the main online guidance for GPs, discourage RADTs use, citing their poor sensitivity and inability to impact on prescribing decisions in acute sore throat infections.
Original languageEnglish
Pages (from-to)437-44
Number of pages8
JournalFamily Practice
Volume26
Issue number6
DOIs
Publication statusPublished - Dec 2009

Keywords

  • Group A streptococcus
  • rapid antigen detection tests
  • sore throat

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