Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study

E Wu, JT Ortiz, P Tejedor, DC Lee, C Bucciarelli-Ducci, P Kansal, JC Carr, TA Holly, D Lloyd-Jones, FJ Klocke, RO Bonow

Research output: Contribution to journalArticle (Academic Journal)peer-review

292 Citations (Scopus)

Abstract

OBJECTIVES: Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling. DESIGN: Prospective cohort study. SETTING: Academic hospital in Chicago, USA. PATIENTS: 122 patients with STEMI following acute percutaneous reperfusion. MAIN OUTCOME MEASURES: Death, recurrent myocardial infarction (MI) and heart failure. METHODS: Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects. RESULTS: Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p
Translated title of the contributionInfarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study
Original languageEnglish
Pages (from-to)730 - 736
Number of pages7
JournalHeart
Volume94
Issue number6
DOIs
Publication statusPublished - Jun 2008

Bibliographical note

Other: Epub 2007 Dec 10

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