Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study

E Wu; JT Ortiz; P Tejedor; DC Lee; C Bucciarelli-Ducci; P Kansal; JC Carr; TA Holly; D Lloyd-Jones; FJ Klocke; RO Bonow

doi:10.1136/hrt.2007.122622

Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study

E Wu, JT Ortiz, P Tejedor, DC Lee, C Bucciarelli-Ducci, P Kansal, JC Carr, TA Holly, D Lloyd-Jones, FJ Klocke, RO Bonow

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

372 Citations (Scopus)

Abstract

OBJECTIVES: Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling. DESIGN: Prospective cohort study. SETTING: Academic hospital in Chicago, USA. PATIENTS: 122 patients with STEMI following acute percutaneous reperfusion. MAIN OUTCOME MEASURES: Death, recurrent myocardial infarction (MI) and heart failure. METHODS: Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects. RESULTS: Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p

Translated title of the contribution	Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study
Original language	English
Pages (from-to)	730 - 736
Number of pages	7
Journal	Heart
Volume	94
Issue number	6
DOIs	https://doi.org/10.1136/hrt.2007.122622
Publication status	Published - Jun 2008

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Other: Epub 2007 Dec 10

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Wu, E., Ortiz, JT., Tejedor, P., Lee, DC., Bucciarelli-Ducci, C., Kansal, P., Carr, JC., Holly, TA., Lloyd-Jones, D., Klocke, FJ., & Bonow, RO. (2008). Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study. Heart, 94(6), 730 - 736. https://doi.org/10.1136/hrt.2007.122622

@article{1e433e691514483792cc434d9c17d20f,

title = "Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study",

abstract = "OBJECTIVES: Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling. DESIGN: Prospective cohort study. SETTING: Academic hospital in Chicago, USA. PATIENTS: 122 patients with STEMI following acute percutaneous reperfusion. MAIN OUTCOME MEASURES: Death, recurrent myocardial infarction (MI) and heart failure. METHODS: Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects. RESULTS: Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p",

author = "E Wu and JT Ortiz and P Tejedor and DC Lee and C Bucciarelli-Ducci and P Kansal and JC Carr and TA Holly and D Lloyd-Jones and FJ Klocke and RO Bonow",

note = "Other: Epub 2007 Dec 10",

year = "2008",

month = jun,

doi = "10.1136/hrt.2007.122622",

language = "English",

volume = "94",

pages = "730 -- 736",

journal = "Heart",

issn = "1355-6037",

publisher = "BMJ Publishing Group",

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Wu, E, Ortiz, JT, Tejedor, P, Lee, DC, Bucciarelli-Ducci, C, Kansal, P, Carr, JC, Holly, TA, Lloyd-Jones, D, Klocke, FJ & Bonow, RO 2008, 'Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study', Heart, vol. 94, no. 6, pp. 730 - 736. https://doi.org/10.1136/hrt.2007.122622

TY - JOUR

T1 - Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study

AU - Wu, E

AU - Ortiz, JT

AU - Tejedor, P

AU - Lee, DC

AU - Bucciarelli-Ducci, C

AU - Kansal, P

AU - Carr, JC

AU - Holly, TA

AU - Lloyd-Jones, D

AU - Klocke, FJ

AU - Bonow, RO

N1 - Other: Epub 2007 Dec 10

PY - 2008/6

Y1 - 2008/6

N2 - OBJECTIVES: Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling. DESIGN: Prospective cohort study. SETTING: Academic hospital in Chicago, USA. PATIENTS: 122 patients with STEMI following acute percutaneous reperfusion. MAIN OUTCOME MEASURES: Death, recurrent myocardial infarction (MI) and heart failure. METHODS: Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects. RESULTS: Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p

AB - OBJECTIVES: Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling. DESIGN: Prospective cohort study. SETTING: Academic hospital in Chicago, USA. PATIENTS: 122 patients with STEMI following acute percutaneous reperfusion. MAIN OUTCOME MEASURES: Death, recurrent myocardial infarction (MI) and heart failure. METHODS: Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects. RESULTS: Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p

UR - https://www.scopus.com/pages/publications/41149172180

U2 - 10.1136/hrt.2007.122622

DO - 10.1136/hrt.2007.122622

M3 - Article (Academic Journal)

C2 - 18070953

SN - 1355-6037

VL - 94

SP - 730

EP - 736

JO - Heart

JF - Heart

IS - 6

ER -

Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study

Abstract

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