Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

Ocular Gene Therapy Inflammation Working Group

doi:10.1167/tvst.10.4.3

Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

Ocular Gene Therapy Inflammation Working Group

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Abstract

Translational Relevance: Subclinical or clinical inflammation often arises during ocular gene therapy with viral vectors. Understanding the biological bases and impacts on efficacy are important for clinical management and the improvement of future therapies.

Original language	English
Article number	3
Pages (from-to)	3
Journal	Translational vision science & technology
Volume	10
Issue number	4
DOIs	https://doi.org/10.1167/tvst.10.4.3
Publication status	Published - 1 Apr 2021

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© 2021 by the authors.

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title = "Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020",

abstract = "Translational Relevance: Subclinical or clinical inflammation often arises during ocular gene therapy with viral vectors. Understanding the biological bases and impacts on efficacy are important for clinical management and the improvement of future therapies.",

author = "{Ocular Gene Therapy Inflammation Working Group} and Chan, {Ying Kai} and Dick, {Andrew D} and Hall, {Sara Mary} and Thomas Langmann and Scribner, {Curtis L} and Mansfield, {Brian C}",

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AU - Dick, Andrew D

AU - Hall, Sara Mary

AU - Langmann, Thomas

AU - Scribner, Curtis L

AU - Mansfield, Brian C

PY - 2021/4/1

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N2 - Translational Relevance: Subclinical or clinical inflammation often arises during ocular gene therapy with viral vectors. Understanding the biological bases and impacts on efficacy are important for clinical management and the improvement of future therapies.

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M3 - Article (Academic Journal)

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Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

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