The MS/MS fragmentation of the alkali metal complexes of monensin A are studied. The increase in alkali metal ionic radii decreases the ability of the Grob-Wharton fragmentation mechanism to occur and reduces the overall degree of fragmentation. Conversely, the electronegativity of the metal cation is related to the number of fragment ions observed.
|Translated title of the contribution||Influence of the Alkali Metal Cation on the Fragmentation of Monensin in ESI-MS/MS|
|Pages (from-to)||363 - 367|
|Number of pages||4|
|Journal||Brazilian Journal of Pharmaceutical Sciences|
|Publication status||Published - Sep 2006|