Insulin and growth factors adaptation to normal puberty

M O Savage; C P Smith; D B Dunger; E A Gale; J M Holly; M A Preece

Insulin and growth factors adaptation to normal puberty

M O Savage, C P Smith, D B Dunger, E A Gale, J M Holly, M A Preece

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

14 Citations (Scopus)

Abstract

Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.

Original language	English
Pages (from-to)	70-73
Number of pages	4
Journal	Hormone Research
Volume	37
Issue number	Suppl 3
Publication status	Published - 1992

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title = "Insulin and growth factors adaptation to normal puberty",

abstract = "Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.",

author = "Savage, {M O} and Smith, {C P} and Dunger, {D B} and Gale, {E A} and Holly, {J M} and Preece, {M A}",

year = "1992",

language = "English",

volume = "37",

pages = "70--73",

journal = "Hormone Research",

issn = "0301-0163",

publisher = "Karger Publishers",

number = "Suppl 3",

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TY - JOUR

T1 - Insulin and growth factors adaptation to normal puberty

AU - Savage, M O

AU - Smith, C P

AU - Dunger, D B

AU - Gale, E A

AU - Holly, J M

AU - Preece, M A

PY - 1992

Y1 - 1992

N2 - Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.

AB - Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.

M3 - Article (Academic Journal)

C2 - 1427646

VL - 37

SP - 70

EP - 73

JO - Hormone Research

JF - Hormone Research

SN - 0301-0163

IS - Suppl 3

ER -

Insulin and growth factors adaptation to normal puberty

Abstract

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