Integrating area-based and national samples in birth cohort studies: the case of Life Study

Harvey Goldstein, Francesco Sera, Peter Elias, Carol Dezateux

Research output: Contribution to journalArticle (Academic Journal)peer-review

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The most recent UK birth cohort study, known as ‘Life Study’ was a longitudinal study planned to involve some 80,000 babies and comprised two components. The largest, the ‘Pregnancy Component’ was to consist of around 60,000 pregnant women who were to be recruited when attending for a routine antenatal ultrasound at selected maternity units in England. The other component, the ‘Birth Component’ was to be a random sample of intended size 20,000 live births across the UK. Recruitment to the cohort was to take place over a period of four years starting in 2015. Innovative sampling procedures had been designed and tested and a synthetic dataset produced with similar characteristics to the anticipated survey data was produced to study the performance of the sampling procedures and explore analysis strategies.
Original languageEnglish
Pages (from-to)281-289
Number of pages10
JournalLongitudinal and Life Course Studies
Issue number3
Publication statusPublished - 25 Jul 2017


  • Cohort studies
  • Non-response
  • Attrition
  • Weighting
  • Probability sampling
  • Research design
  • Longitudinal studies


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