Integrative analysis of array-comparative genomic hybridisation and matched gene expression profiling data reveals novel genes with prognostic significance in oesophageal adenocarcinoma

X Y Goh, J R E Rees, A L Paterson, S F Chin, J C Marioni, V Save, M O'Donovan, P P Eijk, D Alderson, B Ylstra, C Caldas, R C Fitzgerald

Research output: Contribution to journalArticle (Academic Journal)peer-review

61 Citations (Scopus)

Abstract

The incidence of oesophageal adenocarcinoma (OAC) has been increasing rapidly with a dismal survival rate of less than 20%. Understanding the genomic aberrations and biology of this cancer may enhance disease interventions. This study aimed to use genome-wide genomic and expression data to enhance the understanding of OAC pathogenesis and identify groups with differential outcomes.
Original languageEnglish
Pages (from-to)1317-1326
Number of pages10
JournalGut
Volume60
Issue number10
DOIs
Publication statusPublished - 2011

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