Intensive care medicine research agenda on cardiac arrest

Jerry P Nolan, Robert A Berg, Stephen Bernard, Bentley J Bobrow, Clifton W Callaway, Tobias Cronberg, Rudolph W Koster, Peter J Kudenchuk, Graham Nichol, Gavin D Perkins, Tom D Rea, Claudio Sandroni, Jasmeet Soar, Kjetil Sunde, Alain Cariou

Research output: Contribution to journalReview article (Academic Journal)peer-review


Over the last 15 years, treatment of comatose post-cardiac arrest patients has evolved to include therapeutic strategies such as urgent coronary angiography with percutaneous coronary intervention (PCI), targeted temperature management (TTM)-requiring mechanical ventilation and sedation-and more sophisticated and cautious prognostication. In 2015, collaboration between the European Resuscitation Council (ERC) and the European Society for Intensive Care Medicine (ESICM) resulted in the first European guidelines on post-resuscitation care. This review addresses the major recent advances in the treatment of cardiac arrest, recent trials that have challenged current practice and the remaining areas of uncertainty.

Original languageEnglish
Pages (from-to)1282-1293
Number of pages12
JournalIntensive Care Medicine
Issue number9
Publication statusPublished - Sep 2017


  • Biomedical Research
  • Cardiopulmonary Resuscitation/education
  • Coma/therapy
  • Coronary Angiography/methods
  • Critical Care
  • Humans
  • Hypothermia, Induced/methods
  • Neuroprotective Agents/therapeutic use
  • Out-of-Hospital Cardiac Arrest/diagnosis
  • Outcome Assessment, Health Care
  • Percutaneous Coronary Intervention/methods
  • Randomized Controlled Trials as Topic
  • Respiration, Artificial/methods
  • Time-to-Treatment


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