International comparison of trends in patients commencing renal replacement therapy by primary renal disease

Vianda S Stel; Ryan Awadhpersad; Maria Pippias; Manuel Ferrer-Alamar; Patrik Finne; Simon D Fraser; James G Heaf; Marc H Hemmelder; Alberto Martínez-Castelao; Johan de Meester; Runolfur Palsson; Friedrich C Prischl; Mårten Segelmark; Jamie P Traynor; Rafael Santamaria; Anna Varberg Reisaeter; Ziad A Massy; Kitty J Jager

doi:10.1111/nep.13531

International comparison of trends in patients commencing renal replacement therapy by primary renal disease

Vianda S Stel, Ryan Awadhpersad, Maria Pippias, Manuel Ferrer-Alamar, Patrik Finne, Simon D Fraser, James G Heaf, Marc H Hemmelder, Alberto Martínez-Castelao, Johan de Meester, Runolfur Palsson, Friedrich C Prischl, Mårten Segelmark, Jamie P Traynor, Rafael Santamaria, Anna Varberg Reisaeter, Ziad A Massy, Kitty J Jager

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

7 Citations (Scopus)

Abstract

AIM: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD).

METHODS: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95% confidence interval (CI) of the time trends was computed using Joinpoint regression.

RESULTS: There was a significant decrease in the incidence of RRT for ESRD due to diabetes mellitus (DM) in Europe (AAPC = -0.9; 95%CI -1.3; -0.5) and to hypertension/renal vascular disease (HT/RVD) in Australia (AAPC = -1.8; 95%CI -3.3; -0.3), Canada (AAPC = -2.9; 95%CI -4.4; -1.5) and Europe (AAPC = -1.1; 95%CI -2.1; -0.0). A decrease or stabilization was observed for glomerulonephritis in all regions and for autosomal dominant polycystic kidney disease (ADPKD) in all regions except for Malaysia and the Republic of Korea. An increase of 5.2-16.3% was observed for DM, HT/RVD and ADPKD in Malaysia and the Republic of Korea.

CONCLUSION: Large international differences exist in the trends in incidence of RRT by primary renal disease. Mapping of these international trends is the first step in defining the causes and successful preventative measures of CKD.

Original language	English
Pages (from-to)	1064-1076
Number of pages	13
Journal	Nephrology
Volume	24
Issue number	10
DOIs	https://doi.org/10.1111/nep.13531
Publication status	Published - 1 Oct 2019

Bibliographical note

Keywords

Adult
Aged
Diabetic Nephropathies/complications
Female
Global Health/trends
Glomerulonephritis/complications
Humans
Incidence
Kidney Failure, Chronic/epidemiology
Male
Middle Aged
Polycystic Kidney, Autosomal Dominant/complications
Preventive Health Services
Public Health/trends
Renal Replacement Therapy/methods
Risk Factors
Vascular Diseases/complications

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Stel, V. S., Awadhpersad, R., Pippias, M., Ferrer-Alamar, M., Finne, P., Fraser, S. D., Heaf, J. G., Hemmelder, M. H., Martínez-Castelao, A., de Meester, J., Palsson, R., Prischl, F. C., Segelmark, M., Traynor, J. P., Santamaria, R., Reisaeter, A. V., Massy, Z. A., & Jager, K. J. (2019). International comparison of trends in patients commencing renal replacement therapy by primary renal disease. Nephrology, 24(10), 1064-1076. https://doi.org/10.1111/nep.13531

@article{fedc93f06ead41d6a9817e1ef260aed1,

title = "International comparison of trends in patients commencing renal replacement therapy by primary renal disease",

abstract = "AIM: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD).METHODS: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95% confidence interval (CI) of the time trends was computed using Joinpoint regression.RESULTS: There was a significant decrease in the incidence of RRT for ESRD due to diabetes mellitus (DM) in Europe (AAPC = -0.9; 95%CI -1.3; -0.5) and to hypertension/renal vascular disease (HT/RVD) in Australia (AAPC = -1.8; 95%CI -3.3; -0.3), Canada (AAPC = -2.9; 95%CI -4.4; -1.5) and Europe (AAPC = -1.1; 95%CI -2.1; -0.0). A decrease or stabilization was observed for glomerulonephritis in all regions and for autosomal dominant polycystic kidney disease (ADPKD) in all regions except for Malaysia and the Republic of Korea. An increase of 5.2-16.3% was observed for DM, HT/RVD and ADPKD in Malaysia and the Republic of Korea.CONCLUSION: Large international differences exist in the trends in incidence of RRT by primary renal disease. Mapping of these international trends is the first step in defining the causes and successful preventative measures of CKD.",

keywords = "Adult, Aged, Diabetic Nephropathies/complications, Female, Global Health/trends, Glomerulonephritis/complications, Humans, Incidence, Kidney Failure, Chronic/epidemiology, Male, Middle Aged, Polycystic Kidney, Autosomal Dominant/complications, Preventive Health Services, Public Health/trends, Renal Replacement Therapy/methods, Risk Factors, Vascular Diseases/complications",

author = "Stel, {Vianda S} and Ryan Awadhpersad and Maria Pippias and Manuel Ferrer-Alamar and Patrik Finne and Fraser, {Simon D} and Heaf, {James G} and Hemmelder, {Marc H} and Alberto Mart{\'i}nez-Castelao and {de Meester}, Johan and Runolfur Palsson and Prischl, {Friedrich C} and M{\aa}rten Segelmark and Traynor, {Jamie P} and Rafael Santamaria and Reisaeter, {Anna Varberg} and Massy, {Ziad A} and Jager, {Kitty J}",

note = "{\textcopyright} 2018 Asian Pacific Society of Nephrology.",

year = "2019",

month = oct,

day = "1",

doi = "10.1111/nep.13531",

language = "English",

volume = "24",

pages = "1064--1076",

journal = "Nephrology",

issn = "1320-5358",

publisher = "Wiley",

number = "10",

}

Stel, VS, Awadhpersad, R, Pippias, M, Ferrer-Alamar, M, Finne, P, Fraser, SD, Heaf, JG, Hemmelder, MH, Martínez-Castelao, A, de Meester, J, Palsson, R, Prischl, FC, Segelmark, M, Traynor, JP, Santamaria, R, Reisaeter, AV, Massy, ZA & Jager, KJ 2019, 'International comparison of trends in patients commencing renal replacement therapy by primary renal disease', Nephrology, vol. 24, no. 10, pp. 1064-1076. https://doi.org/10.1111/nep.13531

TY - JOUR

T1 - International comparison of trends in patients commencing renal replacement therapy by primary renal disease

AU - Stel, Vianda S

AU - Awadhpersad, Ryan

AU - Pippias, Maria

AU - Ferrer-Alamar, Manuel

AU - Finne, Patrik

AU - Fraser, Simon D

AU - Heaf, James G

AU - Hemmelder, Marc H

AU - Martínez-Castelao, Alberto

AU - de Meester, Johan

AU - Palsson, Runolfur

AU - Prischl, Friedrich C

AU - Segelmark, Mårten

AU - Traynor, Jamie P

AU - Santamaria, Rafael

AU - Reisaeter, Anna Varberg

AU - Massy, Ziad A

AU - Jager, Kitty J

PY - 2019/10/1

Y1 - 2019/10/1

N2 - AIM: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD).METHODS: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95% confidence interval (CI) of the time trends was computed using Joinpoint regression.RESULTS: There was a significant decrease in the incidence of RRT for ESRD due to diabetes mellitus (DM) in Europe (AAPC = -0.9; 95%CI -1.3; -0.5) and to hypertension/renal vascular disease (HT/RVD) in Australia (AAPC = -1.8; 95%CI -3.3; -0.3), Canada (AAPC = -2.9; 95%CI -4.4; -1.5) and Europe (AAPC = -1.1; 95%CI -2.1; -0.0). A decrease or stabilization was observed for glomerulonephritis in all regions and for autosomal dominant polycystic kidney disease (ADPKD) in all regions except for Malaysia and the Republic of Korea. An increase of 5.2-16.3% was observed for DM, HT/RVD and ADPKD in Malaysia and the Republic of Korea.CONCLUSION: Large international differences exist in the trends in incidence of RRT by primary renal disease. Mapping of these international trends is the first step in defining the causes and successful preventative measures of CKD.

AB - AIM: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD).METHODS: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95% confidence interval (CI) of the time trends was computed using Joinpoint regression.RESULTS: There was a significant decrease in the incidence of RRT for ESRD due to diabetes mellitus (DM) in Europe (AAPC = -0.9; 95%CI -1.3; -0.5) and to hypertension/renal vascular disease (HT/RVD) in Australia (AAPC = -1.8; 95%CI -3.3; -0.3), Canada (AAPC = -2.9; 95%CI -4.4; -1.5) and Europe (AAPC = -1.1; 95%CI -2.1; -0.0). A decrease or stabilization was observed for glomerulonephritis in all regions and for autosomal dominant polycystic kidney disease (ADPKD) in all regions except for Malaysia and the Republic of Korea. An increase of 5.2-16.3% was observed for DM, HT/RVD and ADPKD in Malaysia and the Republic of Korea.CONCLUSION: Large international differences exist in the trends in incidence of RRT by primary renal disease. Mapping of these international trends is the first step in defining the causes and successful preventative measures of CKD.

KW - Adult

KW - Aged

KW - Diabetic Nephropathies/complications

KW - Female

KW - Global Health/trends

KW - Glomerulonephritis/complications

KW - Humans

KW - Incidence

KW - Kidney Failure, Chronic/epidemiology

KW - Male

KW - Middle Aged

KW - Polycystic Kidney, Autosomal Dominant/complications

KW - Preventive Health Services

KW - Public Health/trends

KW - Renal Replacement Therapy/methods

KW - Risk Factors

KW - Vascular Diseases/complications

U2 - 10.1111/nep.13531

DO - 10.1111/nep.13531

M3 - Article (Academic Journal)

C2 - 30456883

VL - 24

SP - 1064

EP - 1076

JO - Nephrology

JF - Nephrology

SN - 1320-5358

IS - 10

ER -

International comparison of trends in patients commencing renal replacement therapy by primary renal disease

Abstract

Bibliographical note

Keywords

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