Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

Rajesh Katare; Andrea Caporali; Lorena Zentilin; Elisa Avolio; Graciela Sala-Newby; Atsuhiko Oikawa; Daniela Cesselli; Antonio Paolo Beltrami; Mauro Giacca; Costanza Emanueli; Paolo Madeddu

doi:10.1161/CIRCRESAHA

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

Rajesh Katare, Andrea Caporali, Lorena Zentilin, Elisa Avolio, Graciela Sala-Newby, Atsuhiko Oikawa, Daniela Cesselli, Antonio Paolo Beltrami, Mauro Giacca, Costanza Emanueli, Paolo Madeddu

Research output: Contribution to journal › Article (Academic Journal) › peer-review

108 Citations (Scopus)

Abstract

Studies in transgenic mice showed the key role of (Pim-1) (proviral integration site for Moloney murine leukemia virus-1) in the control of cardiomyocyte function and viability.

Translated title of the contribution	Intravenous Gene Therapy With PIM-1 Via a Cardiotropic Viral Vector Halts the Progression of Diabetic Cardiomyopathy Through Promotion of Prosurvival Signaling
Original language	English
Pages (from-to)	1238 - 1251
Number of pages	14
Journal	Circulation Research
Volume	108
Issue number	10
DOIs	https://doi.org/10.1161/CIRCRESAHA
Publication status	Published - May 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1161/CIRCRESAHA

http://circres.ahajournals.org/cgi/content/full/108/10/1238

Handle.net

Persistent link

Cite this

Katare, R., Caporali, A., Zentilin, L., Avolio, E., Sala-Newby, G., Oikawa, A., Cesselli, D., Beltrami, A. P., Giacca, M., Emanueli, C., & Madeddu, P. (2011). Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling. Circulation Research, 108(10), 1238 - 1251. https://doi.org/10.1161/CIRCRESAHA

@article{f4704b5dfeb942618f401b7356b28319,

title = "Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling",

abstract = "Studies in transgenic mice showed the key role of (Pim-1) (proviral integration site for Moloney murine leukemia virus-1) in the control of cardiomyocyte function and viability.",

author = "Rajesh Katare and Andrea Caporali and Lorena Zentilin and Elisa Avolio and Graciela Sala-Newby and Atsuhiko Oikawa and Daniela Cesselli and Beltrami, {Antonio Paolo} and Mauro Giacca and Costanza Emanueli and Paolo Madeddu",

year = "2011",

month = may,

doi = "10.1161/CIRCRESAHA",

language = "English",

volume = "108",

pages = "1238 -- 1251",

journal = "Circulation Research",

issn = "1524-4571",

publisher = "Lippincott Williams and Wilkins",

number = "10",

}

Katare, R, Caporali, A, Zentilin, L, Avolio, E, Sala-Newby, G, Oikawa, A, Cesselli, D, Beltrami, AP, Giacca, M, Emanueli, C & Madeddu, P 2011, 'Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling', Circulation Research, vol. 108, no. 10, pp. 1238 - 1251. https://doi.org/10.1161/CIRCRESAHA

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling. / Katare, Rajesh; Caporali, Andrea; Zentilin, Lorena et al.
In: Circulation Research, Vol. 108, No. 10, 05.2011, p. 1238 - 1251.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

AU - Katare, Rajesh

AU - Caporali, Andrea

AU - Zentilin, Lorena

AU - Avolio, Elisa

AU - Sala-Newby, Graciela

AU - Oikawa, Atsuhiko

AU - Cesselli, Daniela

AU - Beltrami, Antonio Paolo

AU - Giacca, Mauro

AU - Emanueli, Costanza

AU - Madeddu, Paolo

PY - 2011/5

Y1 - 2011/5

N2 - Studies in transgenic mice showed the key role of (Pim-1) (proviral integration site for Moloney murine leukemia virus-1) in the control of cardiomyocyte function and viability.

AB - Studies in transgenic mice showed the key role of (Pim-1) (proviral integration site for Moloney murine leukemia virus-1) in the control of cardiomyocyte function and viability.

U2 - 10.1161/CIRCRESAHA

DO - 10.1161/CIRCRESAHA

M3 - Article (Academic Journal)

C2 - 21474815

SN - 1524-4571

VL - 108

SP - 1238

EP - 1251

JO - Circulation Research

JF - Circulation Research

IS - 10

ER -

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

Abstract

UN SDGs

Access to Document

Handle.net

Fingerprint

Cite this