Ionic liquids in oligosaccharide synthesis: towards mucin-type glycan probes

MC Galan; A Corfield

doi:10.1042/BST0381368

Ionic liquids in oligosaccharide synthesis: towards mucin-type glycan probes

MC Galan , A Corfield

Research output: Contribution to journal › Article (Academic Journal) › peer-review

18 Citations (Scopus)

Abstract

The present article provides an overview on mucins and their role in biological processes, while aiming to familiarize readers with the current tools available for the synthesis of structurally defined mucin-type glycan probes including the advantages and potential applications of using ionic liquids in the synthesis of this important class of oligosaccharides. Furthermore, we also highlight recent developments in glycoarray technology that can enable high-sensitivity and high-throughput analysis of this important class of protein-carbohydrate interactions.

Translated title of the contribution	Ionic liquids in oligosaccharide synthesis: towards mucin-type glycan probes
Original language	English
Pages (from-to)	1368 - 1376
Number of pages	11
Journal	Biochemical Society Transactions
Volume	38(5)
DOIs	https://doi.org/10.1042/BST0381368
Publication status	Published - Oct 2010

Bibliographical note

Publisher: Transactions

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10.1042/BST0381368

http://www.biochemsoctrans.org/bst/038/1368/0381368.pdf

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SYNTHESIS OF MUCIN TYPE O-GLYCANS VIA IONIC CATCH AND RELEASE METHODOLOGY. TOWARDS THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES
Galan, M. C. (Principal Investigator)
Engineering and Physical Sciences Research Council
1/03/08 → 1/07/11
Project: Research

Cite this

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title = "Ionic liquids in oligosaccharide synthesis: towards mucin-type glycan probes",

abstract = "The present article provides an overview on mucins and their role in biological processes, while aiming to familiarize readers with the current tools available for the synthesis of structurally defined mucin-type glycan probes including the advantages and potential applications of using ionic liquids in the synthesis of this important class of oligosaccharides. Furthermore, we also highlight recent developments in glycoarray technology that can enable high-sensitivity and high-throughput analysis of this important class of protein-carbohydrate interactions.",

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AU - Corfield, A

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N2 - The present article provides an overview on mucins and their role in biological processes, while aiming to familiarize readers with the current tools available for the synthesis of structurally defined mucin-type glycan probes including the advantages and potential applications of using ionic liquids in the synthesis of this important class of oligosaccharides. Furthermore, we also highlight recent developments in glycoarray technology that can enable high-sensitivity and high-throughput analysis of this important class of protein-carbohydrate interactions.

AB - The present article provides an overview on mucins and their role in biological processes, while aiming to familiarize readers with the current tools available for the synthesis of structurally defined mucin-type glycan probes including the advantages and potential applications of using ionic liquids in the synthesis of this important class of oligosaccharides. Furthermore, we also highlight recent developments in glycoarray technology that can enable high-sensitivity and high-throughput analysis of this important class of protein-carbohydrate interactions.

U2 - 10.1042/BST0381368

DO - 10.1042/BST0381368

M3 - Article (Academic Journal)

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VL - 38(5)

SP - 1368

EP - 1376

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

ER -

Ionic liquids in oligosaccharide synthesis: towards mucin-type glycan probes

Abstract

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SYNTHESIS OF MUCIN TYPE O-GLYCANS VIA IONIC CATCH AND RELEASE METHODOLOGY. TOWARDS THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES

Cite this