Iron-Catalysed Reduction of Olefins using a Borohydride Reagent

Tom S. Carter, Lea Guiet, Dominik J. Frank, James West, Stephen P. Thomas*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

18 Citations (Scopus)

Abstract

The iron-catalysed reduction of olefins has been achieved using a simple iron salt and sodium triethylborohydride. A wide range of mono- and trans-1,2-disubstituted alkenes have been reduced (91100%) using 25mol% iron(II) triflate, 1mol% N-methyl-2-pyrrolidinone and 4equivalents of sodium triethylborohydride. The reduction of alkynes to alkanes is also reported (up to 84%). Significantly, the reduction of trisubstituted alkenes has also been achieved (6086%).

Original languageEnglish
Pages (from-to)880-884
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number5
DOIs
Publication statusPublished - Mar 2013

Keywords

  • catalysis
  • hydrogenation
  • iron
  • olefins
  • reduction
  • CROSS-COUPLING REACTIONS
  • ASYMMETRIC TRANSFER HYDROGENATION
  • GRIGNARD-REAGENTS
  • ARYL IODIDES
  • COMPLEXES
  • ALKENES
  • ALKYNES
  • ACETOPHENONE
  • HALIDES
  • FE

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