Projects per year
The iron-catalysed reduction of olefins has been achieved using a simple iron salt and sodium triethylborohydride. A wide range of mono- and trans-1,2-disubstituted alkenes have been reduced (91100%) using 25mol% iron(II) triflate, 1mol% N-methyl-2-pyrrolidinone and 4equivalents of sodium triethylborohydride. The reduction of alkynes to alkanes is also reported (up to 84%). Significantly, the reduction of trisubstituted alkenes has also been achieved (6086%).
- CROSS-COUPLING REACTIONS
- ASYMMETRIC TRANSFER HYDROGENATION
- ARYL IODIDES