Abstract
Simple catalysts formed in situ from iron chloride and a wide range of monodentate and bidentate phosphines and arsines have been screened in the coupling of alkyl halides bearing -hydrogens with aryl Grignard reagents. The best of these show excellent activity, as do catalysts formed in situ with monodentate trialkyl and triaryl phosphite ligands. N-heterocyclic carbene-based precatalysts, either preformed or made in situ, also show excellent performance.
Translated title of the contribution | Iron-phosphine, -phosphite, -arsine, and -carbene catalysts for the coupling of primary and secondary alkyl halides with aryl Grignard reagents |
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Original language | English |
Pages (from-to) | 1104 - 1110 |
Number of pages | 7 |
Journal | Journal of Organic Chemistry |
Volume | 71 (3) |
DOIs | |
Publication status | Published - Feb 2006 |