Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study

Jane E. Ferrie; Mika Kivimaki; Martin J. Shipley; George Davey Smith; Marianna Virtanen

doi:10.1016/j.atherosclerosis.2012.12.027

Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study

Jane E. Ferrie^*, Mika Kivimaki, Martin J. Shipley, George Davey Smith, Marianna Virtanen

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

45 Citations (Scopus)

Abstract

Objective: This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously.

Methods: Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events).

Results: Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88).

Original language	English
Pages (from-to)	178-181
Number of pages	4
Journal	Atherosclerosis
Volume	227
Issue number	1
DOIs	https://doi.org/10.1016/j.atherosclerosis.2012.12.027
Publication status	Published - Mar 2013

Keywords

Job insecurity
Stress
Incident coronary heart disease
Angina
Middle-aged
Prospective
ACUTE MYOCARDIAL-INFARCTION
ST-ELEVATION
FOLLOW-UP
HEALTH
CONSEQUENCES
COUNTRIES
MORTALITY
ANGINA
RATES
WOMEN

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1/09/07 → 1/09/13
Project: Research

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title = "Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study",

abstract = "Objective: This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously.Methods: Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events).Results: Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88).Conclusion: This study suggests that job insecurity may adversely affect coronary health. (C) 2013 Elsevier Ireland Ltd. All rights reserved.",

keywords = "Job insecurity, Stress, Incident coronary heart disease, Angina, Middle-aged, Prospective, ACUTE MYOCARDIAL-INFARCTION, ST-ELEVATION, FOLLOW-UP, HEALTH, CONSEQUENCES, COUNTRIES, MORTALITY, ANGINA, RATES, WOMEN",

author = "Ferrie, {Jane E.} and Mika Kivimaki and Shipley, {Martin J.} and Smith, {George Davey} and Marianna Virtanen",

year = "2013",

month = mar,

doi = "10.1016/j.atherosclerosis.2012.12.027",

language = "English",

volume = "227",

pages = "178--181",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier",

number = "1",

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T1 - Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study

AU - Ferrie, Jane E.

AU - Kivimaki, Mika

AU - Shipley, Martin J.

AU - Smith, George Davey

AU - Virtanen, Marianna

PY - 2013/3

Y1 - 2013/3

N2 - Objective: This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously.Methods: Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events).Results: Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88).Conclusion: This study suggests that job insecurity may adversely affect coronary health. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

AB - Objective: This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously.Methods: Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events).Results: Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88).Conclusion: This study suggests that job insecurity may adversely affect coronary health. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

KW - Job insecurity

KW - Stress

KW - Incident coronary heart disease

KW - Angina

KW - Middle-aged

KW - Prospective

KW - ACUTE MYOCARDIAL-INFARCTION

KW - ST-ELEVATION

KW - FOLLOW-UP

KW - HEALTH

KW - CONSEQUENCES

KW - COUNTRIES

KW - MORTALITY

KW - ANGINA

KW - RATES

KW - WOMEN

U2 - 10.1016/j.atherosclerosis.2012.12.027

DO - 10.1016/j.atherosclerosis.2012.12.027

M3 - Article (Academic Journal)

C2 - 23332775

SN - 0021-9150

VL - 227

SP - 178

EP - 181

JO - Atherosclerosis

JF - Atherosclerosis

IS - 1

ER -

Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study

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Keywords

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