TY - JOUR
T1 - Lack of association between aortic sclerosis and left ventricular hypertrophy in elderly subjects
AU - Nightingale, Angus K
AU - Sverdlov, Aaron L
AU - Rajendran, Sharmalar
AU - Mishra, Kumaril
AU - Heresztyn, Tamila
AU - Ngo, Doan T M
AU - Horowitz, John D
N1 - Copyright © 2010. Published by Elsevier Ireland Ltd.
PY - 2011
Y1 - 2011
N2 - The presence of aortic sclerosis has been associated with increased LV mass, particularly in hypertensive subjects. However, aortic sclerosis has also been associated with endothelial dysfunction, which may provide stimuli for development of left ventricular hypertrophy independent of afterload. Thus, we have sought to determine whether aortic sclerosis is a determinant of increased left ventricular mass in a non-hypertensive cohort of aging subjects.
AB - The presence of aortic sclerosis has been associated with increased LV mass, particularly in hypertensive subjects. However, aortic sclerosis has also been associated with endothelial dysfunction, which may provide stimuli for development of left ventricular hypertrophy independent of afterload. Thus, we have sought to determine whether aortic sclerosis is a determinant of increased left ventricular mass in a non-hypertensive cohort of aging subjects.
U2 - 10.1016/j.ijcard.2010.02.024
DO - 10.1016/j.ijcard.2010.02.024
M3 - Article (Academic Journal)
C2 - 20236713
SN - 1874-1754
VL - 150
SP - 33
EP - 38
JO - International Journal of Cardiology
JF - International Journal of Cardiology
IS - 1
ER -