Lifetime cardiovascular management of patients with previous Kawasaki Disease

Paul Brogan, Jane C Burns, Jacqueline Cornish, Vinod Diwakar, Despina Eleftheriou , John B Gordon, Huon Hamilton Gray, Thomas William Johnson, Michael Levin, Iqbal Malik, Philip MacCarthy, Rachael McCormack, Owen Miller, Robert M R Tulloh

Research output: Contribution to journalArticle (Academic Journal)peer-review

8 Citations (Scopus)
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Abstract

Kawasaki Disease (KD) is an inflammatory disorder of young children, associated with vasculitis of the coronary arteries with subsequent aneurysm formation in up to one third of untreated patients. Those who develop aneurysms are at life-long risk of coronary thrombosis or the development of stenotic lesions, which may lead to myocardial ischemia, infarction or death. The incidence of KD is increasing worldwide, and in more economically developed countries KD is now the commonest cause of acquired heart disease in children. However, many clinicians in the UK are unaware of the disorder and its long-term cardiac complications, potentially leading to late diagnosis, delayed treatment and poorer outcomes. Increasing numbers of patients who suffered KD in childhood are transitioning to the care of adult services where there is significantly less awareness and experience of the condition than in paediatric services. The aim of this document is to provide guidance on the long-term management of patients who have vascular complications of KD, and guidance on the emergency management of acute coronary complications. Guidance on the management of acute KD is published elsewhere.
Original languageEnglish
Article number315925
Number of pages10
JournalHeart
Volume2019
Early online date16 Dec 2019
DOIs
Publication statusPublished - 16 Dec 2019

Bibliographical note

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords

  • Kawasaki disease
  • transitional care
  • person specific protocol
  • cardiovascular risk
  • lifetime cardiovascular management
  • acute coronary syndrome
  • coronary artery aneurysm
  • late sequelae

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