Long-term leisure-time physical activity and serum metabolome

Urho M Kujala; Ville-Petteri Mäkinen; Ilkka Heinonen; Pasi Soininen; Antti J Kangas; Tuija H Leskinen; Paavo Rahkila; Peter Würtz; Vuokko Kovanen; Sulin Cheng; Sarianna Sipilä; Mirja Hirvensalo; Risto Telama; Tuija Tammelin; Markku J Savolainen; Anneli Pouta; Paul F O'Reilly; Pekka Mäntyselkä; Jorma Viikari; Mika Kähönen; Terho Lehtimäki; Paul Elliott; Mauno J Vanhala; Olli T Raitakari; Marjo-Riitta Järvelin; Jaakko Kaprio; Heikki Kainulainen; Mika Ala-Korpela

doi:10.1161/CIRCULATIONAHA.112.105551

Long-term leisure-time physical activity and serum metabolome

Urho M Kujala, Ville-Petteri Mäkinen, Ilkka Heinonen, Pasi Soininen, Antti J Kangas, Tuija H Leskinen, Paavo Rahkila, Peter Würtz, Vuokko Kovanen, Sulin Cheng, Sarianna Sipilä, Mirja Hirvensalo, Risto Telama, Tuija Tammelin, Markku J Savolainen, Anneli Pouta, Paul F O'Reilly, Pekka Mäntyselkä, Jorma Viikari, Mika KähönenTerho Lehtimäki, Paul Elliott, Mauno J Vanhala, Olli T Raitakari, Marjo-Riitta Järvelin, Jaakko Kaprio, Heikki Kainulainen, Mika Ala-Korpela

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

183 Citations (Scopus)

Abstract

Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk.

Original language	English
Pages (from-to)	340-348
Number of pages	9
Journal	Circulation
Volume	127
Issue number	3
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.112.105551
Publication status	Published - 22 Jan 2013

Keywords

Young Adult
Humans
Fatty Acids
Twins, Dizygotic
Blood Glucose
Isoleucine
Leisure Activities
Metabolome
Twins, Monozygotic
Motor Activity
Adult
Cohort Studies
Lipoproteins
Middle Aged
Adolescent
Female
Male

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10.1161/CIRCULATIONAHA.112.105551

http://circ.ahajournals.org/content/127/3/340

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Kujala, U. M., Mäkinen, V.-P., Heinonen, I., Soininen, P., Kangas, A. J., Leskinen, T. H., Rahkila, P., Würtz, P., Kovanen, V., Cheng, S., Sipilä, S., Hirvensalo, M., Telama, R., Tammelin, T., Savolainen, M. J., Pouta, A., O'Reilly, P. F., Mäntyselkä, P., Viikari, J., ... Ala-Korpela, M. (2013). Long-term leisure-time physical activity and serum metabolome. Circulation, 127(3), 340-348. https://doi.org/10.1161/CIRCULATIONAHA.112.105551

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abstract = "Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk.",

keywords = "Young Adult, Humans, Fatty Acids, Twins, Dizygotic, Blood Glucose, Isoleucine, Leisure Activities, Metabolome, Twins, Monozygotic, Motor Activity, Adult, Cohort Studies, Lipoproteins, Middle Aged, Adolescent, Female, Male",

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doi = "10.1161/CIRCULATIONAHA.112.105551",

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Kujala, UM, Mäkinen, V-P, Heinonen, I, Soininen, P, Kangas, AJ, Leskinen, TH, Rahkila, P, Würtz, P, Kovanen, V, Cheng, S, Sipilä, S, Hirvensalo, M, Telama, R, Tammelin, T, Savolainen, MJ, Pouta, A, O'Reilly, PF, Mäntyselkä, P, Viikari, J, Kähönen, M, Lehtimäki, T, Elliott, P, Vanhala, MJ, Raitakari, OT, Järvelin, M-R, Kaprio, J, Kainulainen, H & Ala-Korpela, M 2013, 'Long-term leisure-time physical activity and serum metabolome', Circulation, vol. 127, no. 3, pp. 340-348. https://doi.org/10.1161/CIRCULATIONAHA.112.105551

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T1 - Long-term leisure-time physical activity and serum metabolome

AU - Kujala, Urho M

AU - Mäkinen, Ville-Petteri

AU - Heinonen, Ilkka

AU - Soininen, Pasi

AU - Kangas, Antti J

AU - Leskinen, Tuija H

AU - Rahkila, Paavo

AU - Würtz, Peter

AU - Kovanen, Vuokko

AU - Cheng, Sulin

AU - Sipilä, Sarianna

AU - Hirvensalo, Mirja

AU - Telama, Risto

AU - Tammelin, Tuija

AU - Savolainen, Markku J

AU - Pouta, Anneli

AU - O'Reilly, Paul F

AU - Mäntyselkä, Pekka

AU - Viikari, Jorma

AU - Kähönen, Mika

AU - Lehtimäki, Terho

AU - Elliott, Paul

AU - Vanhala, Mauno J

AU - Raitakari, Olli T

AU - Järvelin, Marjo-Riitta

AU - Kaprio, Jaakko

AU - Kainulainen, Heikki

AU - Ala-Korpela, Mika

PY - 2013/1/22

Y1 - 2013/1/22

N2 - Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk.

AB - Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk.

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KW - Humans

KW - Fatty Acids

KW - Twins, Dizygotic

KW - Blood Glucose

KW - Isoleucine

KW - Leisure Activities

KW - Metabolome

KW - Twins, Monozygotic

KW - Motor Activity

KW - Adult

KW - Cohort Studies

KW - Lipoproteins

KW - Middle Aged

KW - Adolescent

KW - Female

KW - Male

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U2 - 10.1161/CIRCULATIONAHA.112.105551

DO - 10.1161/CIRCULATIONAHA.112.105551

M3 - Article (Academic Journal)

C2 - 23258601

SN - 0009-7322

VL - 127

SP - 340

EP - 348

JO - Circulation

JF - Circulation

IS - 3

ER -

Long-term leisure-time physical activity and serum metabolome

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Keywords

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CENTRE FOR CASUAL ANALYSES IN TRANSLATIONAL EPIDEMIOLOGY (CAiTE)

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Long-term leisure-time physical activity and serum metabolome

Abstract

Keywords

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