Long-term potentiation in the hippocampus: discovery, mechanisms and function

Tim V.P. Bliss, Graham Collingridge, Richard G M Morris, Klaus G Reymann

Research output: Contribution to journalArticle (Academic Journal)peer-review

14 Citations (Scopus)
630 Downloads (Pure)


In this review we reflect upon our contributions to the study of the properties and mechanisms of long-term potentiation (LTP) and describe some of the major influences on our work. We then go on to consider whether LTP has fulfilled its early promise of providing a compelling account of the synaptic basis of learning and memory.
Original languageEnglish
Pages (from-to)A103–A120
Number of pages18
Issue number3
Early online date15 Aug 2018
Publication statusPublished - 28 Aug 2018


  • LTP
  • hippocampus
  • NMDA receptor
  • protein synthesis
  • memory

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