LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

Justina Ronkainen, Rozenn Nedelec, Angelica Atehortua, Zhanna Balkhiyarova, Anna Cascarano, Vien Ngoc Dang, Ahmed Elhakeem, Esther van Enckevort, Ana Luiza Goncalves Soares, Sido Haakma, Mila Halonen, Katharina F Heil, Anni Heiskala, Eleanor Hyde, Bénédicte Jacquemin, Elina Keikkala, Jules Kerckhoffs, Anton Klavus, Joanna A Kopinska, Johanna LepeuleFrancesca Marazzi, Irina Motoc, Mari Naatanen, Anton Ribbenstedt, Amanda Rundblad, Otto Savolainen, Nicholas John Timpson, Vakebtuba Simonetti, Nina de Toro Eadie, Evangelia Tzala, Anna Ulrich, Thomas Wright, Iman Zarei, Enrico d/Amico, Federico Belotti, Carl Brunius, Sylvain P Sebert*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

4 Citations (Scopus)
29 Downloads (Pure)


The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.
Original languageEnglish
Article numbere184
Number of pages12
JournalEnvironmental Epidemiology
Issue number1
Early online date28 Dec 2021
Publication statusPublished - 1 Feb 2022

Bibliographical note

Funding Information:
Supported by the European Commission through the Horizon 2020 research and innovation programme under grant agreement number 874739.

Publisher Copyright:
© 2022 Wolters Kluwer Health. All rights reserved.


  • Exposome
  • Cardio-metabolic and vascular health
  • Life-course pathways
  • European research consortium


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