LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

Justina Ronkainen; Rozenn Nedelec; Angelica Atehortua; Zhanna Balkhiyarova; Anna Cascarano; Vien Ngoc Dang; Ahmed  Elhakeem; Esther van Enckevort; Ana Luiza  Goncalves Soares; Sido Haakma; Mila Halonen; Katharina F Heil; Anni Heiskala; Eleanor Hyde; Bénédicte Jacquemin; Elina Keikkala; Jules Kerckhoffs; Anton Klavus; Joanna A Kopinska; Johanna Lepeule; Francesca Marazzi; Irina Motoc; Mari Naatanen; Anton Ribbenstedt; Amanda Rundblad; Otto Savolainen; Nicholas John  Timpson; Vakebtuba Simonetti; Nina de Toro Eadie; Evangelia  Tzala; Anna Ulrich; Thomas Wright; Iman Zarei; Enrico d/Amico; Federico Belotti; Carl  Brunius; Sylvain P Sebert

doi:10.1097/EE9.0000000000000184

LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

Justina Ronkainen
, Rozenn Nedelec
, Angelica Atehortua
, Zhanna Balkhiyarova
, Anna Cascarano
, Vien Ngoc Dang
, Ahmed Elhakeem
, Esther van Enckevort
, Ana Luiza Goncalves Soares
, Sido Haakma
, Mila Halonen
, Katharina F Heil
, Anni Heiskala
, Eleanor Hyde
, Bénédicte Jacquemin
, Elina Keikkala
, Jules Kerckhoffs
, Anton Klavus
, Joanna A Kopinska
, Johanna Lepeule

Francesca Marazzi, Irina Motoc, Mari Naatanen, Anton Ribbenstedt, Amanda Rundblad, Otto Savolainen, Nicholas John Timpson, Vakebtuba Simonetti, Nina de Toro Eadie, Evangelia Tzala, Anna Ulrich, Thomas Wright, Iman Zarei, Enrico d/Amico, Federico Belotti, Carl Brunius, Sylvain P Sebert^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

25 Citations (Scopus)

95 Downloads (Pure)

Abstract

The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.

Original language	English
Article number	e184
Number of pages	12
Journal	Environmental Epidemiology
Volume	6
Issue number	1
Early online date	28 Dec 2021
DOIs	https://doi.org/10.1097/EE9.0000000000000184
Publication status	Published - 1 Feb 2022

Bibliographical note

Funding Information:
Supported by the European Commission through the Horizon 2020 research and innovation programme under grant agreement number 874739.

Publisher Copyright:
© 2022 Wolters Kluwer Health. All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Exposome
Cardio-metabolic and vascular health
Life-course pathways
European research consortium

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Ronkainen, J., Nedelec, R., Atehortua, A., Balkhiyarova, Z., Cascarano, A., Dang, V. N., Elhakeem, A., van Enckevort, E., Goncalves Soares, A. L., Haakma, S., Halonen, M., Heil, K. F., Heiskala, A., Hyde, E., Jacquemin, B., Keikkala, E., Kerckhoffs, J., Klavus, A., Kopinska, J. A., ... Sebert, S. P. (2022). LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases. Environmental Epidemiology, 6(1), Article e184. https://doi.org/10.1097/EE9.0000000000000184

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title = "LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases",

abstract = "The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.",

keywords = "Exposome, Cardio-metabolic and vascular health, Life-course pathways, European research consortium",

author = "Justina Ronkainen and Rozenn Nedelec and Angelica Atehortua and Zhanna Balkhiyarova and Anna Cascarano and Dang, \{Vien Ngoc\} and Ahmed Elhakeem and \{van Enckevort\}, Esther and \{Goncalves Soares\}, \{Ana Luiza\} and Sido Haakma and Mila Halonen and Heil, \{Katharina F\} and Anni Heiskala and Eleanor Hyde and B{\'e}n{\'e}dicte Jacquemin and Elina Keikkala and Jules Kerckhoffs and Anton Klavus and Kopinska, \{Joanna A\} and Johanna Lepeule and Francesca Marazzi and Irina Motoc and Mari Naatanen and Anton Ribbenstedt and Amanda Rundblad and Otto Savolainen and Timpson, \{Nicholas John\} and Vakebtuba Simonetti and \{Toro Eadie\}, \{Nina de\} and Evangelia Tzala and Anna Ulrich and Thomas Wright and Iman Zarei and Enrico d/Amico and Federico Belotti and Carl Brunius and Sebert, \{Sylvain P\}",

note = "Funding Information: Supported by the European Commission through the Horizon 2020 research and innovation programme under grant agreement number 874739. Publisher Copyright: {\textcopyright} 2022 Wolters Kluwer Health. All rights reserved.",

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day = "1",

doi = "10.1097/EE9.0000000000000184",

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Ronkainen, J, Nedelec, R, Atehortua, A, Balkhiyarova, Z, Cascarano, A, Dang, VN, Elhakeem, A, van Enckevort, E, Goncalves Soares, AL, Haakma, S, Halonen, M, Heil, KF, Heiskala, A, Hyde, E, Jacquemin, B, Keikkala, E, Kerckhoffs, J, Klavus, A, Kopinska, JA, Lepeule, J, Marazzi, F, Motoc, I, Naatanen, M, Ribbenstedt, A, Rundblad, A, Savolainen, O, Timpson, NJ, Simonetti, V, Toro Eadie, ND, Tzala, E, Ulrich, A, Wright, T, Zarei, I, d/Amico, E, Belotti, F, Brunius, C & Sebert, SP 2022, 'LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases', Environmental Epidemiology, vol. 6, no. 1, e184. https://doi.org/10.1097/EE9.0000000000000184

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AU - Ronkainen, Justina

AU - Nedelec, Rozenn

AU - Atehortua, Angelica

AU - Balkhiyarova, Zhanna

AU - Cascarano, Anna

AU - Dang, Vien Ngoc

AU - Elhakeem, Ahmed

AU - van Enckevort, Esther

AU - Goncalves Soares, Ana Luiza

AU - Haakma, Sido

AU - Halonen, Mila

AU - Heil, Katharina F

AU - Heiskala, Anni

AU - Hyde, Eleanor

AU - Jacquemin, Bénédicte

AU - Keikkala, Elina

AU - Kerckhoffs, Jules

AU - Klavus, Anton

AU - Kopinska, Joanna A

AU - Lepeule, Johanna

AU - Marazzi, Francesca

AU - Motoc, Irina

AU - Naatanen, Mari

AU - Ribbenstedt, Anton

AU - Rundblad, Amanda

AU - Savolainen, Otto

AU - Timpson, Nicholas John

AU - Simonetti, Vakebtuba

AU - Toro Eadie, Nina de

AU - Tzala, Evangelia

AU - Ulrich, Anna

AU - Wright, Thomas

AU - Zarei, Iman

AU - d/Amico, Enrico

AU - Belotti, Federico

AU - Brunius, Carl

AU - Sebert, Sylvain P

N1 - Funding Information: Supported by the European Commission through the Horizon 2020 research and innovation programme under grant agreement number 874739. Publisher Copyright: © 2022 Wolters Kluwer Health. All rights reserved.

PY - 2022/2/1

Y1 - 2022/2/1

N2 - The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.

AB - The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar societies globally characterized by rural-to-urban migration, modernization of agricultural practices, and transportation, climate change, and aging. Evidence suggests that these changes are related to each other, although the social and biological mechanisms as well as their interactions have yet to be uncovered. LongITools, as one of the 9 projects included in the European Human Exposome Network, will tackle this environmental health equation linking multidimensional environmental exposures to the occurrence of cardiovascular and metabolic noncommunicable diseases.

KW - Exposome

KW - Cardio-metabolic and vascular health

KW - Life-course pathways

KW - European research consortium

U2 - 10.1097/EE9.0000000000000184

DO - 10.1097/EE9.0000000000000184

M3 - Article (Academic Journal)

C2 - 35169663

SN - 2474-7882

VL - 6

JO - Environmental Epidemiology

JF - Environmental Epidemiology

IS - 1

M1 - e184

ER -

LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

Abstract

Bibliographical note

UN SDGs

Keywords

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