Longitudinal associations of sauna bathing with inflammation and oxidative stress: the KIHD prospective cohort study

Setor Kunutsor*, Tanjaniina Laukkanen, Jari Laukkanen

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

12 Citations (Scopus)
143 Downloads (Pure)

Abstract

Purpose: We sought to determine cross-sectional and longitudinal associations of frequency of sauna bathing with high sensitivity C-reactive protein (hsCRP), fibrinogen, leucocyte count and gamma-glutamyltransferase (GGT).

Design: Baseline sauna bathing habits were assessed in 2269 men aged 42–61 years. Concentrations of hsCRP, fibrinogen, leucocyte count, and GGT were determined at baseline and 11 years later. The associations of sauna bathing frequency with baseline and 11-year hsCRP, fibrinogen, leucocyte count, and GGT levels were examined using robust multivariate regression analyses.

Results:In baseline analysis, 4–7 sauna sessions/week (compared with 1 sauna session/week) was associated with −0.84 mg/l (95% CI, −1.55, −0.14; p = .019) lower hsCRP; −0.07 g/l (95% CI, −0.15, 0.02; p = .112) lower fibrinogen; and −0.28 × 109/l (95% CI, −0.51, −0.06; p = .015) lower leucocyte count, after multivariable adjustment. In longitudinal analysis, the corresponding estimates were −1.66 mg/l (95% CI, −3.13, −0.19; p = .027); −0.16 g/l (95% CI, −0.31, −0.02; p = .031); and −0.49 × 109/l (95% CI, −0.85, −0.14; p = .007) respectively. Sauna bathing frequency was not associated with GGT at baseline and 11 years.

Conclusion: Observational evidence supports the hypothesis that reduction in inflammation may be one of the pathways linking frequent sauna bathing with decreased risk of acute and chronic disease conditions.
Original languageEnglish
Pages (from-to)437-442
Number of pages6
JournalAnnals of Medicine
Volume50
Issue number5
Early online date24 Jul 2018
DOIs
Publication statusPublished - Jul 2018

Keywords

  • cohort study
  • inflammation
  • oxidative stress
  • Sauna bathing

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