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Long-term Quality of Life Following Vestibular Schwannoma Excision Via the Translabyrinthine Approach

Research output: Contribution to journalArticle

  • Stephen J. Broomfield
  • Ashish K. Mandavia
  • Jack S. Nicholson
  • Osama Mahmoud
  • Andrew T. King
  • Scott A. Rutherford
  • Richard T. Ramsden
Original languageEnglish
Pages (from-to)1165-1173
Number of pages9
JournalOtology and Neurotology
Issue number8
Early online date1 Sep 2017
DateAccepted/In press - 23 Jun 2017
DateE-pub ahead of print - 1 Sep 2017
DatePublished (current) - 1 Sep 2017


Objective: To assess post-operative quality of life (QOL) and other patient-reported outcomes following surgery for vestibular schwannoma.

Study Design: Cross-sectional retrospective case review using postal questionnaires.

Setting: Tertiary referral centre.

Patients: Five hundred consecutive patients undergoing surgery for vestibular

Intervention(s): Patients undergoing surgery via the translabyrinthine approach
(excluding neurofibromatosis type 2) under the senior author, with a minimum of five years follow-up, were included.

Main Outcome Measure(s): QOL was assessed using the Short Form 36 (SF-36)
questionnaire and a disease-specific survey to assess patients' subjective outcomes.

Results: The SF-36 scores in this group were significantly lower than the general UK population, though 24% of respondents reported a subjective improvement in overall QOL. Tumours larger than 4cm were related to a reduced SF-36 total mental component score (P = 0.037). Increased age at time of surgery correlated with a reduced physical component of QOL (correlation coefficient = -0.26) and an improved mental component (correlation coefficient = 0.26). Subjective reports of post-operative symptoms and return to work, driving and social activities were similar to other published studies. 35% of patients reported vivid dreams or nightmares following surgery; the first reported incidence of this phenomenon in a large group of vestibular schwannoma patients.

Conclusions: Generic measures of QOL in patients following translabyrinthine surgery for vestibular schwannoma do not always match subjective reports, reflecting the complexity of QOL assessment and the range of outcomes in this group. Increased time since surgery appears to be associated with an improvement in mental health.

    Research areas

  • Acoustic neuroma (vestibular schwannoma), Quality of life, Surgery

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    Rights statement: This is the accepted author manuscript (AAM). The final published version (version of record) is available online via Wolters Kluwer at . Please refer to any applicable terms of use of the publisher.

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