Abstract
It has been proposed that the dissociation between growth hormone secretion and insulin-like growth factor-I (IGF-I) concentrations in insulin-dependent diabetes mellitus arises because of partial resistance at the GH receptor. In order to explore this hypothesis further we have examined the relations between IGF-I, GH-binding protein (GHBP), and GH secretion in normal subjects and patients with diabetes during puberty.
Original language | English |
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Pages (from-to) | 517-24 |
Number of pages | 8 |
Journal | Clinical Endocrinology |
Volume | 41 |
Issue number | 4 |
Publication status | Published - 1994 |