Low-Frequency Mechanical Ventilation During Cardiopulmonary Bypass

Research output: Chapter in Book/Report/Conference proceedingChapter in a book


Pulmonary dysfunction during cardiac surgery may range from subclinical changes
up to acute lung injury and acute respiratory distress syndrome. Causative factors include inflammation, pulmonary ischemia and reperfusion-related injury, blood contact with the surface of cardiopulmonary bypass (CPB) machinery, endotoxemia, surgical trauma, blood loss, and transfusion. Strikingly thin, the laminated, tripartite construction of the blood–gas barrier promotes gas exchange by passive diffusion.
Original languageEnglish
Title of host publicationPrinciples of Pulmonary Protection in Heart Surgery
PublisherSpringer London
Publication statusPublished - 2010

Structured keywords

  • Centre for Surgical Research


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