Abstract
Pulmonary dysfunction during cardiac surgery may range from subclinical changes
up to acute lung injury and acute respiratory distress syndrome. Causative factors include inflammation, pulmonary ischemia and reperfusion-related injury, blood contact with the surface of cardiopulmonary bypass (CPB) machinery, endotoxemia, surgical trauma, blood loss, and transfusion. Strikingly thin, the laminated, tripartite construction of the blood–gas barrier promotes gas exchange by passive diffusion.
up to acute lung injury and acute respiratory distress syndrome. Causative factors include inflammation, pulmonary ischemia and reperfusion-related injury, blood contact with the surface of cardiopulmonary bypass (CPB) machinery, endotoxemia, surgical trauma, blood loss, and transfusion. Strikingly thin, the laminated, tripartite construction of the blood–gas barrier promotes gas exchange by passive diffusion.
| Original language | English |
|---|---|
| Title of host publication | Principles of Pulmonary Protection in Heart Surgery |
| Publisher | Springer London |
| Pages | 367-375 |
| Publication status | Published - 2010 |
Structured keywords
- Centre for Surgical Research