Magnetizing DNA and Proteins Using Responsive Surfactants

Paul Brown; Asad M. Khan; James P Armstrong; Adam W. Perriman; Craig P. Butts; Julian Eastoe

doi:10.1002/adma.201202685

Magnetizing DNA and Proteins Using Responsive Surfactants

Paul Brown, Asad M. Khan, James P Armstrong, Adam W. Perriman, Craig P. Butts, Julian Eastoe^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

64 Citations (Scopus)

Abstract

DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

Original language	English
Pages (from-to)	6244-6247
Number of pages	4
Journal	Advanced Materials
Volume	24
Issue number	46
Early online date	4 Sep 2012
DOIs	https://doi.org/10.1002/adma.201202685
Publication status	Published - 4 Dec 2012

Keywords

DYNAMIC LIGHT-SCATTERING
ACID
BINDING
PURIFICATION
magnetic manipulation
MYOGLOBIN
DELIVERY
COMPACTION
NANOPARTICLES
SEPARATION
magnetic surfactants
CATIONIC SURFACTANT
DNA compaction

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10.1002/adma.201202685

http://onlinelibrary.wiley.com/doi/10.1002/adma.201202685/abstract

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title = "Magnetizing DNA and Proteins Using Responsive Surfactants",

abstract = "DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching {"}on{"} and {"}off{"} of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.",

keywords = "DYNAMIC LIGHT-SCATTERING, ACID, BINDING, PURIFICATION, magnetic manipulation, MYOGLOBIN, DELIVERY, COMPACTION, NANOPARTICLES, SEPARATION, magnetic surfactants, CATIONIC SURFACTANT, DNA compaction",

author = "Paul Brown and Khan, {Asad M.} and Armstrong, {James P} and Perriman, {Adam W.} and Butts, {Craig P.} and Julian Eastoe",

year = "2012",

month = dec,

day = "4",

doi = "10.1002/adma.201202685",

language = "English",

volume = "24",

pages = "6244--6247",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley",

number = "46",

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TY - JOUR

T1 - Magnetizing DNA and Proteins Using Responsive Surfactants

AU - Brown, Paul

AU - Khan, Asad M.

AU - Armstrong, James P

AU - Perriman, Adam W.

AU - Butts, Craig P.

AU - Eastoe, Julian

PY - 2012/12/4

Y1 - 2012/12/4

N2 - DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

AB - DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

KW - DYNAMIC LIGHT-SCATTERING

KW - ACID

KW - BINDING

KW - PURIFICATION

KW - magnetic manipulation

KW - MYOGLOBIN

KW - DELIVERY

KW - COMPACTION

KW - NANOPARTICLES

KW - SEPARATION

KW - magnetic surfactants

KW - CATIONIC SURFACTANT

KW - DNA compaction

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84870523896&partnerID=8YFLogxK

U2 - 10.1002/adma.201202685

DO - 10.1002/adma.201202685

M3 - Article (Academic Journal)

C2 - 22945776

VL - 24

SP - 6244

EP - 6247

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

IS - 46

ER -

Magnetizing DNA and Proteins Using Responsive Surfactants

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Chemical and biophysical studies of ionic protein fluids.

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Magnetizing DNA and Proteins Using Responsive Surfactants

Abstract

Keywords

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Chemical and biophysical studies of ionic protein fluids.

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