Magnetizing DNA and Proteins Using Responsive Surfactants

Paul Brown, Asad M. Khan, James P Armstrong, Adam W. Perriman, Craig P. Butts, Julian Eastoe*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

50 Citations (Scopus)

Abstract

DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

Original languageEnglish
Pages (from-to)6244-6247
Number of pages4
JournalAdvanced Materials
Volume24
Issue number46
Early online date4 Sep 2012
DOIs
Publication statusPublished - 4 Dec 2012

Keywords

  • DYNAMIC LIGHT-SCATTERING
  • ACID
  • BINDING
  • PURIFICATION
  • magnetic manipulation
  • MYOGLOBIN
  • DELIVERY
  • COMPACTION
  • NANOPARTICLES
  • SEPARATION
  • magnetic surfactants
  • CATIONIC SURFACTANT
  • DNA compaction

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