Magnetizing DNA and Proteins Using Responsive Surfactants

Paul Brown; Asad M. Khan; James P Armstrong; Adam W. Perriman; Craig P. Butts; Julian Eastoe

doi:10.1002/adma.201202685

Magnetizing DNA and Proteins Using Responsive Surfactants

Paul Brown, Asad M. Khan, James P Armstrong, Adam W. Perriman, Craig P. Butts, Julian Eastoe^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal)

50 Citations (Scopus)

Abstract

DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.

Original language	English
Pages (from-to)	6244-6247
Number of pages	4
Journal	Advanced Materials
Volume	24
Issue number	46
Early online date	4 Sep 2012
DOIs	https://doi.org/10.1002/adma.201202685
Publication status	Published - 4 Dec 2012

Keywords

DYNAMIC LIGHT-SCATTERING
ACID
BINDING
PURIFICATION
magnetic manipulation
MYOGLOBIN
DELIVERY
COMPACTION
NANOPARTICLES
SEPARATION
magnetic surfactants
CATIONIC SURFACTANT
DNA compaction

Access to Document

10.1002/adma.201202685

Projects

1 Finished

Chemical and biophysical studies of ionic protein fluids.

Perriman, A. W.

1/05/10 → 1/05/13

Project: Research

Cite this

Brown, P., Khan, A. M., Armstrong, J. P., Perriman, A. W., Butts, C. P., & Eastoe, J. (2012). Magnetizing DNA and Proteins Using Responsive Surfactants. Advanced Materials, 24(46), 6244-6247. https://doi.org/10.1002/adma.201202685

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AU - Khan, Asad M.

AU - Armstrong, James P

AU - Perriman, Adam W.

AU - Butts, Craig P.

AU - Eastoe, Julian

PY - 2012/12/4

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KW - PURIFICATION

KW - magnetic manipulation

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KW - DELIVERY

KW - COMPACTION

KW - NANOPARTICLES

KW - SEPARATION

KW - magnetic surfactants

KW - CATIONIC SURFACTANT

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