Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

H Gonçalves; Rebecca M Pearson; B L Horta; D A González-Chica; E Castilho; M Damiani; R C Lima; D P Gigante; Fernando C. Barros; Alan Stein; C G Victora

doi:10.1017/S0033291715001956

Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

H Gonçalves, Rebecca M Pearson, B L Horta, D A González-Chica, E Castilho, M Damiani, R C Lima, D P Gigante, Fernando C. Barros, Alan Stein, C G Victora

Research output: Contribution to journal › Article (Academic Journal) › peer-review

29 Citations (Scopus)

293 Downloads (Pure)

Abstract

BACKGROUND: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood.

METHOD: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated.

RESULTS: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71-7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers.

CONCLUSIONS: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

Original language	English
Pages (from-to)	415-424
Number of pages	10
Journal	Psychological Medicine
Volume	46
Issue number	2
Early online date	12 Oct 2015
DOIs	https://doi.org/10.1017/S0033291715001956
Publication status	Published - Jan 2016

Keywords

cohort study
common mental disorder
intergenerational
mental health
offspring

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1017/S0033291715001956

Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via Cambridge University Press at DOI: 10.1017/S0033291715001956. Please refer to any applicable terms of use of the publisher.
Final published version, 298 KBLicence: CC BY

Handle.net

Persistent link

Dr Rebecca M Pearson
- Rebecca.Pearsonbristol.acuk
- Bristol Medical School (PHS) - Senior Lecturer in Psychiatric Epidemiology
- Bristol Population Health Science Institute
- Centre for Academic Mental Health
Person: Academic , Member

Cite this

Gonçalves, H., Pearson, R. M., Horta, B. L., González-Chica, D. A., Castilho, E., Damiani, M., Lima, R. C., Gigante, D. P., Barros, F. C., Stein, A., & Victora, C. G. (2016). Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood. Psychological Medicine, 46(2), 415-424. https://doi.org/10.1017/S0033291715001956

@article{c96e00ee31354792b803679a8d05c8de,

title = "Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood",

abstract = "BACKGROUND: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood.METHOD: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated.RESULTS: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71-7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers.CONCLUSIONS: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.",

keywords = "cohort study, common mental disorder, intergenerational, mental health, offspring",

author = "H Gon{\c c}alves and Pearson, {Rebecca M} and Horta, {B L} and Gonz{\'a}lez-Chica, {D A} and E Castilho and M Damiani and Lima, {R C} and Gigante, {D P} and Barros, {Fernando C.} and Alan Stein and Victora, {C G}",

year = "2016",

month = jan,

doi = "10.1017/S0033291715001956",

language = "English",

volume = "46",

pages = "415--424",

journal = "Psychological Medicine",

issn = "0033-2917",

publisher = "Cambridge University Press",

number = "2",

}

TY - JOUR

T1 - Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

AU - Gonçalves, H

AU - Pearson, Rebecca M

AU - Horta, B L

AU - González-Chica, D A

AU - Castilho, E

AU - Damiani, M

AU - Lima, R C

AU - Gigante, D P

AU - Barros, Fernando C.

AU - Stein, Alan

AU - Victora, C G

PY - 2016/1

Y1 - 2016/1

N2 - BACKGROUND: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood.METHOD: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated.RESULTS: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71-7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers.CONCLUSIONS: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

AB - BACKGROUND: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood.METHOD: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated.RESULTS: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71-7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers.CONCLUSIONS: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

KW - cohort study

KW - common mental disorder

KW - intergenerational

KW - mental health

KW - offspring

U2 - 10.1017/S0033291715001956

DO - 10.1017/S0033291715001956

M3 - Article (Academic Journal)

C2 - 26456404

SN - 0033-2917

VL - 46

SP - 415

EP - 424

JO - Psychological Medicine

JF - Psychological Medicine

IS - 2

ER -

Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

Abstract

Keywords

UN SDGs

Access to Document

Handle.net

Fingerprint

Profiles

Dr Rebecca M Pearson

Cite this