Maternal dietary patterns during pregnancy and intelligence quotients in the offspring at 8 years of age: Findings from the ALSPAC cohort

Ana Amélia Freitas-Vilela*, Rebecca M. Pearson, Pauline Emmett, Jon Heron, Andrew D A C Smith, Alan Emond, Joseph R. Hibbeln, Maria Beatriz Trindade Castro, Gilberto Kac

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

11 Citations (Scopus)
252 Downloads (Pure)

Abstract

Dietary intake during pregnancy may influence child neurodevelopment and cognitive function. This study aims to investigate the associations between dietary patterns obtained in pregnancy and intelligence quotients (IQ) among offspring at 8 years of age. Pregnant women enrolled in the Avon Longitudinal Study of Parents and Children completed a food frequency questionnaire at 32 weeks' gestation (n = 12,195). Dietary patterns were obtained by cluster analysis. Three clusters best described women's diets during pregnancy: "fruit and vegetables," "meat and potatoes," and "white bread and coffee." The offspring's IQ at 8 years of age was assessed using the Wechsler Intelligence Scale for Children. Models, using variables correlated to IQ data, were performed to impute missing values. Linear regression models were employed to investigate associations between the maternal clusters and IQ in childhood. Children of women who were classified in the meat and potatoes cluster and white bread and coffee cluster during pregnancy had lower average verbal (β = -1.74; p < .001 and β = -3.05; p < .001), performance (β = -1.26; p = .011 and β = -1.75; p < .001), and full-scale IQ (β = -1.74; p < .001 and β = -2.79; p < .001) at 8 years of age when compared to children of mothers in the fruit and vegetables cluster in imputed models of IQ and all confounders, after adjustment for a wide range of known confounders including maternal education. The pregnant women who were classified in the fruit and vegetables cluster had offspring with higher average IQ compared with offspring of mothers in the meat and potatoes cluster and white bread and coffee cluster.

Original languageEnglish
Article numbere12431
Pages (from-to)1-11
Number of pages11
JournalMaternal and Child Nutrition
Volume2017
Early online date2 Mar 2017
DOIs
Publication statusE-pub ahead of print - 2 Mar 2017

Keywords

  • ALSPAC
  • Children
  • Cluster analysis
  • Dietary patterns
  • Intelligence quotient
  • Pregnancy

Fingerprint

Dive into the research topics of 'Maternal dietary patterns during pregnancy and intelligence quotients in the offspring at 8 years of age: Findings from the ALSPAC cohort'. Together they form a unique fingerprint.

Cite this